Results 101 to 110 of about 295,403 (308)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

TL-moments and L-moments Estimation of the Generalized Logistic Distribution

Journal of Mathematics Research, 2011
La distribución logística generalizada (GLO) se ha utilizado ampliamente en la evaluación de eventos de valor extremo y también es popular en el análisis de riesgos hidrológicos. Al estimar los eventos de alto período de retorno, censurar los datos desde abajo podría ser ventajoso ya que las inundaciones pequeñas son menos significativas que las ...
Ummi Nadiah Ahmad, Ani Shabri, Zalmiyah Zakaria   +2 more
openaire   +4 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

The effect of active exoskeleton support with different lumbar-to-hip support ratios on spinal musculoskeletal loading and lumbar kinematics during lifting

Wearable Technologies
While active back-support exoskeletons can reduce mechanical loading of the spine, current designs include only one pair of actuated hip joints combined with a rigid structure between the pelvis and trunk attachments, restricting lumbar flexion and ...
Niels P. Brouwer, Ali Tabasi, Feng Hu, Idsart Kingma, Wietse van Dijk, Mohamed Irfan Mohamed Refai, Herman van der Kooij, Jaap H. van Dieën   +7 more
doaj   +1 more source

Radiative τ leptonic decays and the possibility to determine the τ dipole moments

EPJ Web of Conferences, 2016
Precise data on radiative leptonic τ decays offer the opportunity to probe the electromagnetic properties of the τ and may allow to determine its anomalous magnetic moment which, in spite of its precise Standard Model prediction, has never been measured.
Fael Matteo
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Frequency analysis of maximum daily rainfalls via L-moment approach

, 2009
Knowledge related to distributions of rainfall amounts are of great importance for the design of water related structures. The greater problem faced by the hydrologists and engineers is identifying the best distribution form for regional data.
Shabri, Ani, Mohd. Ariff, Noratiqah, Ani Shabri,, Noratiqah Mohd Ariff,   +3 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Frequency distribution models and L-moment characteristics of floods in turkish rivers

, 2015
Mühendislik sistemlerindeki taşkın kontrolü amaçlı yapıların boyutlandırılmasında taşkın frekans analizi büyük önem taşımaktadır. Bu tür yapıların tasarımında uygulanacak projelendirme kriterleri önemli ölçüde taşkın olayının olasılık dağılım türüne ve ...
Niftelizade, Orhan
core