Results 101 to 110 of about 10,531,857 (299)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

ESTIMASI PARAMETER PADA STANDARD CAPM (CAPITAL ASSETS PRICING MODEL) DENGAN METODE GMM (GENERALIZED METHOD OF MOMENTS)

open access: yes, 2014
Tujuan utama dari analisis regresi adalah menduga parameter yang tidak diketahui dalam model. Tiga metode estimasi populer yang banyak digunakan adalah kuadrat terkecil (Least-Squares) dan likelihood maksimum (Maximumum Likelihood) dan metode momen ...
ESTIMASI PARAMETER PADA STANDARD CAPM (CAPITAL ASSETS PRICING MODEL) DENGAN METODE GMM (GENERALIZED METHOD OF MOMENTS)
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

leomartire/MVG-Moments: Alpha

open access: yes, 2018
A Python/Matlab module to compute moments of multivariate Gaussian distributions, including non-trivial ...
Léo Martire
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Magnetic and Spectroscopic Studies of the Synthesized Metal Complexes of Bis(Pyridine-2-carbo) Hydrazide and Their Antimicrobial Studies

open access: yesE-Journal of Chemistry, 2012
Cobalt(II), Nickel(II), Copper(II) and Manganese(II) complexes, having the general composition {M(L)2X2}, have been synthesized [where L= bis(pyridine-2-carbo) hydrazide(L), and X = Cl–].
Netra Pal Singh, Anu, Jagvir Singh
doaj   +1 more source

Method of L-moments

open access: yes, 2011
katedra: KAP; přílohy: 1 CD ROM; rozsah: 72L-moments are analogy to the conventional moments and they are based on the linear combinations of order statistics.
Šimková, Tereza
core  

Generalized energy inequalities and higher multifractal moments

open access: yes, 2014
We present a class of generalized energy inequalities and indicate their use in investigating higher multifractal moments, in particular Lq-dimensions of images of measures under Brownian processes, Lq-dimensions of almost self-affine measures, and moments
Falconer, Kenneth John, Kenneth Falconer
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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