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Novel dTDP-l-Rhamnose Synthetic Enzymes (RmlABCD) From Saccharothrix syringae CGMCC 4.1716 for One-Pot Four-Enzyme Synthesis of dTDP-l-Rhamnose [PDF]

open access: yesFrontiers in Microbiology, 2021
Deoxythymidine diphospho-l-rhamnose (dTDP-l-rhamnose) is used by prokaryotic rhamnosyltransferases as the glycosyl donor for the synthesis of rhamnose-containing polysaccharides and compounds that have potential in pharmaceutical development, so its ...
Shida Yang   +11 more
doaj   +2 more sources

The l-rhamnose-dependent regulator RhaS and its target promoters from Escherichia coli expand the genetic toolkit for regulatable gene expression in the acetic acid bacterium Gluconobacter oxydans [PDF]

open access: yesFrontiers in Microbiology, 2022
For regulatable target gene expression in the acetic acid bacterium (AAB) Gluconobacter oxydans only recently the first plasmids became available. These systems solely enable AraC- and TetR-dependent induction. In this study we showed that the l-rhamnose-
Philipp Moritz Fricke   +6 more
doaj   +2 more sources

Catabolism of l-rhamnose in A. nidulans proceeds via the non-phosphorylated pathway and is glucose repressed by a CreA-independent mechanism [PDF]

open access: yesMicrobial Cell Factories, 2020
l-rhamnose (6-deoxy-mannose) occurs in nature mainly as a component of certain plant structural polysaccharides and bioactive metabolites but has also been found in some microorganisms and animals.
Andrew P. MacCabe   +3 more
doaj   +2 more sources

Rhamnose-Containing Compounds: Biosynthesis and Applications

open access: yesMolecules, 2022
Rhamnose-associated molecules are attracting attention because they are present in bacteria but not mammals, making them potentially useful as antibacterial agents. Additionally, they are also valuable for tumor immunotherapy.
Guofeng Gu, Siqiang Li, Lizhen Wang
exaly   +3 more sources

Synthesis and Evaluation of Fluorine-18-Labeled L-Rhamnose Derivatives [PDF]

open access: yesMolecules, 2023
The use of radiolabeled glucose for PET imaging resulted in the most commonly used tracer in the clinic, 2-deoxy-2-[18F]fluoroglucose (FDG). More recently, other radiolabeled sugars have been reported for various applications, including imaging tumors ...
Xiang Zhang   +9 more
doaj   +2 more sources

Characterization of RmlABCD Enzymes from Marine Bacteria and Efficient Synthesis of dTDP-L-Rhamnose [PDF]

open access: yesMicroorganisms
dTDP-L-rhamnose (Deoxythymidine diphospho-L-rhamnose) is a crucial active sugar nucleotide that serves as the key glycosyl donor for the synthesis of rhamnose-containing polysaccharides in bacteria, holding broad application potential in pathogen ...
Jinghua Li   +9 more
doaj   +2 more sources

L-Rhamnose Dehydrogenase LraA of Aspergillus niger Shows High Substrate Specificity Matching Its Expression Profile [PDF]

open access: yesJournal of Fungi
L-rhamnose is one of the main monomeric sugars of rhamnogalacturonan I and II, which are polysaccharide components of pectin. In the ascomycete fungus Aspergillus niger it is metabolized through the non-phosphorylated L-rhamnose pathway, of which the ...
Agata Terebieniec   +4 more
doaj   +2 more sources

L-Rhamnose Globally Changes the Transcriptome of Planktonic and Biofilm Escherichia coli Cells and Modulates Biofilm Growth [PDF]

open access: yesMicroorganisms
L-rhamnose, a naturally abundant sugar, plays diverse biological roles in bacteria, influencing biofilm formation and pathogenesis. This study investigates the global impact of L-rhamnose on the transcriptome and biofilm formation of PHL628 E. coli under
Charlotte E. Hantus   +5 more
doaj   +2 more sources

Mechanistic Study of L-Rhamnose Monohydrate Dehydration Using Terahertz Spectroscopy and Density Functional Theory [PDF]

open access: yesMolecules
L-rhamnose has recently gained attention for its potential to enhance vaccine antigenicity. To optimize its use as a vaccine adjuvant, it is important to understand the dehydration behavior of L-rhamnose monohydrate, which plays a critical role in ...
Bingxin Yan   +5 more
doaj   +2 more sources

A genetically encoded L-rhamnose biosensor for monitoring marine polysaccharide depolymerization [PDF]

open access: yesApplied Microbiology and Biotechnology
Marine macroalgae, particularly their complex polysaccharides, are an untapped renewable source of high-quality monosaccharides and related building blocks.
Yannick L. Wolf   +2 more
doaj   +2 more sources

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