Results 61 to 70 of about 493,432 (269)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Molecular identification based on coat protein sequences of the Barley yellow dwarf virus from Brazil

open access: yesScientia Agricola, 2013
Yellow dwarf disease, one of the most important diseases of cereal crops worldwide, is caused by virus species belonging to the Luteoviridae family.
Talita Bernardon Mar   +4 more
doaj   +1 more source

Dimension-Five Operators in Grand Unified Theories

open access: yes, 2007
Extensions of the standard model with low-energy supersymmetry generically allow baryon- and lepton-number violating operators of dimension four and five, yielding rapid proton decay.
Sayre, Joshua   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Molecular identification of phytoplasmas associated with some weeds in West Azarbaijan province, Iran

open access: yesActa Agriculturae Slovenica, 2016
During field surveys in 2013 and 2014, about 14 weed plants showing phytoplasma diseases symptoms including yellowing and witches’broom were collected and tested by polymerase chain reaction (PCR) using universal primers for 16SrRNA starting by primer ...
Samaneh ZIBADOOST, Mina RASTGOU
doaj   +1 more source

The mass of the Higgs boson in the trinification subgroup of E6

open access: yes, 2012
The extension of the standard model to SU(3)_L x SU(3)_R x SU(3)_C is considered. Spontaneous symmetry breaking requires two Higgs field multiplets with a strong hierarchical structure of vacuum expectation values.
B. Stech   +3 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

A-models in three and four dimensions [PDF]

open access: yes, 2010
We introduce and study a new 3d Topological Field Theory which can be associated to any compact real manifold X. This TFT is analogous to the 2d A-model and reduces to it upon compactification on an interval with suitable boundary conditions.
Kapustin, Anton, Vyas, Ketan
core   +2 more sources

Aspects of symmetry breaking in SO(10) GUTs

open access: yes, 2011
I review some recent results on the Higgs sector of minimal SO(10) grand unified theories both with and without supersymmetry. It is shown that nonsupersymmetric SO(10) with just one adjoint triggering the first stage of the symmetry breaking does ...
Bertolini S   +3 more
core   +1 more source

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