Results 41 to 50 of about 57,431 (202)

Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B [PDF]

Blood, 2012
Abstract Ribosomal protein (RP) mutations in diseases such as 5q− syndrome both disrupt hematopoiesis and increase the risk of developing hematologic malignancy. However, the mechanism by which RP mutations increase cancer risk has remained an important unanswered question.
Shuyun, Rao, Sang-Yun, Lee, Alejandro, Gutierrez, Jacqueline, Perrigoue, Roshan J, Thapa, Zhigang, Tu, John R, Jeffers, Michele, Rhodes, Stephen, Anderson, Tamas, Oravecz, Stephen P, Hunger, Roman A, Timakhov, Rugang, Zhang, Siddharth, Balachandran, Gerard P, Zambetti, Joseph R, Testa, A Thomas, Look, David L, Wiest   +17 more
openaire   +2 more sources

Homoleptic and Heteroleptic Borylones L1‐B(Ph)‐L2

Angewandte Chemie International Edition, EarlyView.
Density functional theory and CCSD(T) calculations reveal that homoleptic and heteroleptic borylones L1–B(Ph)–L2 are thermodynamically accessible. Remarkably, the homoleptic borylones B(Ph)(N2)2 and B(Ph)(SPh2)2 exhibit higher bond dissociation energies than the related carbones.
Qin Ma, Wei Li, Ya Hu, Lili Zhao, Gernot Frenking   +4 more
wiley   +1 more source

Financial Stability of Insurance Companies in Selected CEE Countries

Business Systems Research, 2019
Background: Financial stability or soundness of insurance companies has gained importance over the years, especially after the financial crisis of 2008. Various stakeholders such as policy makers, regulators, the insured, etc.
Pavić Kramarić Tomislava, Miletić Marko, Kožul Blaževski Renata   +2 more
doaj   +1 more source

Comment on “Opinion: Can uncertainty in climate sensitivity be narrowed further?” by Sherwood and Forest (2024) [PDF]

Atmospheric Chemistry and Physics
This comment addresses assertions made by Sherwood and Forest (2024) (SF24) regarding the narrowing of the range of equilibrium climate sensitivity (ECS).
N. Lewis
doaj   +1 more source

Flavours and Infra-red Instability in Holography

, 2017
Within a phenomenological holographic model in $(4+1)$-bulk dimensions, defined by Einstein-gravity with a negative cosmological constant, coupled to a Dirac-Born-Infeld and a Chern-Simons term, we explore the fate of BF-bound violation for a probe ...
Kundu, Arnab
core   +1 more source

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

British Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon, Hinke Huisman‐Siebinga, Shelby Barnett, Paul Wetherell, Pamela Kearns, Brenda Gibson, Nicholas Heaney, Owen Smith, André Baruchel, Arnaud Petit, Andrew Moore, Kayode Ogungbenro, Alwin D. R. Huitema, Gareth J. Veal   +13 more
wiley   +1 more source

Resistance to 16-Membered Macrolides, Tiamulin and Lincomycin in a Swine Isolate of Acholeplasma laidlawii

Antibiotics, 2021
Acholeplasma (A.) laidlawii is an opportunistic pathogen with the ability to disseminate resistance determinants to antibiotics; however, its resistance to macrolides has been less studied.
María M. Tavío, Ana S. Ramírez, Carlos Poveda, Rubén S. Rosales, Cristina F. Malla, José B. Poveda   +5 more
doaj   +1 more source

Critical-exponent Sobolev norms and the slice theorem for the quotient space of connections [PDF]

, 1999
The use of certain critical-exponent Sobolev norms is an important feature of methods employed by Taubes to solve the anti-self-dual and similar non-linear elliptic partial differential equations. Indeed, the estimates one can obtain using these critical-
Aubin, Donaldson, Feehan, Freed, Lawson, Mitter, Parker, Parker, Paul M.N. Feehan, Singer, Stein, Taubes, Taubes, Taubes, Taubes, Taubes, Uhlenbeck   +16 more
core   +4 more sources

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

Food Safety and Health, EarlyView.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei, Mengqi Qu, Ziru Yang, Xuebin Xu, Yanan Wang   +4 more
wiley   +1 more source

Competition and Productivity Evolutions in Industry Sector [PDF]

پژوهشهای اقتصادی, 2012
The importance of productivity has made it to be one of the most serious discussions in industrial organizing. In economic literature, however, there are some arguments on the role of market structure in productivity changes.
Vahid Mehrbani
doaj