Results 81 to 90 of about 7,231 (208)

Barriers and opportunities in implementation of Lean Manufacturing tools in the ceramic industry

open access: yesProduction Engineering Archives, 2018
The concept of lean management in an organization, improving products and processes using the Lean Manufacturing concept, is discussed in this paper. Striving for excellence is the key factor in maintaining competitiveness on the market.
Kleszcz Daniel
doaj   +1 more source

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1744-1759, June 2026.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet   +17 more
wiley   +1 more source

Ex-ante impact evaluation of the L23 rice genotype on the colombian Altillanura plains [PDF]

open access: yes, 2019
Introduction. The Colombian Altillanura is going through a process of transformation, marked by the expansion of its agricultural border. In the region, it is being implemented a research agenda that seeks to develop and validate promising technologies ...
Labarta, Ricardo Antonio   +4 more
core  

LEAN Production issues in the organization of the company - the first stage

open access: yesProduction Engineering Archives, 2018
Today’s market determinants and most importantly, very dynamically changing customer requirements significantly shortened the product life cycle. This situation reflects in companies by common extension of the assortment offered and personalised serial ...
Mazur Magdalena, Momeni Hassan
doaj   +1 more source

Nonlinear Vibration Characteristic Analysis of Electric Vehicle–Road Coupling System

open access: yesInternational Journal of Mechanical System Dynamics, Volume 6, Issue 2, Page 267-281, June 2026.
ABSTRACT In‐wheel motor drive is the developing direction of automobile electrification and intelligence. However, the increased unsprung mass in in‐wheel motor‐driven electric vehicles (IWMEVs) leads to higher dynamic tire loads, thereby intensifying vehicle–road coupling interactions. To address this problem, an 11‐degree‐of‐freedom nonlinear dynamic
Guizhen Feng, Shaohua Li, Xuewei Wang
wiley   +1 more source

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system

open access: yesJournal of Cell Science, 2018
ABSTRACT Glutamate-rich WD40 repeat-containing 1 (GRWD1) is a Cdt1-binding protein that promotes mini-chromosome maintenance (MCM) loading through its histone chaperone activity. GRWD1 acts as a tumor-promoting factor by downregulating p53 (also known as TP53) via the RPL11–MDM2–p53 axis.
Shinya Watanabe   +8 more
openaire   +2 more sources

Understanding Water Activity in Deep Eutectic Solvents: Experimental Screening, Thermodynamic Modeling, and QSAR Predictions

open access: yesChemistrySelect, Volume 11, Issue 21, 4 June 2026.
Water activity (aw) was measured in eight DESs (10–90 wt% water). Strong DES–water interactions persist to ∼50 wt%, after which structure collapses toward aqueous‐like behavior. Redlich–Kister, Wilson, and COSMO‐RS models showed limited performance, whereas QSAR modeling using COSMOtherm‐derived σ‐profile descriptors significantly improved aw ...
Marko Rogošić   +6 more
wiley   +1 more source

A novel approach to the study of surface oxidation states and oxidation of transition metals by Auger electron spectroscopy [PDF]

open access: yes, 1980
L23 M45 M45/L23 M23 M45, L23 M45 M45/L23 M23 M23 and L23 M23 M45/L23 M23 M23 Auger intensity ratios in transition metal oxides and sulphides are shown to be directly related to the number of valence electrons in the metal as well as to its oxidation ...
Hegde, M. S.   +2 more
core   +1 more source

Low‐Dose Electron Total Scattering Analysis Resolves Non‐Crystalline Phase Separation in Polymer Semiconductors and Device Multilayers

open access: yesSmall Methods, Volume 10, Issue 11, 8 June 2026.
The performance of polymer blend semiconductors is governed by both the degree of phase separation and crystallization, but these two aspects have remained unresolved. We report methods for mapping amorphous‐amorphous as well as amorphous‐crystalline phase separation in polyfluorene‐based polymer blends using spatially resolved nanobeam electron total ...
Sang T. Pham   +2 more
wiley   +1 more source

Relative quantification of AGO2 and RdR6 expression in Nicotiana benthamiana infected with different viruses, with PP2A, F-BOX and L23 in combination as reference genes. [PDF]

open access: yes, 2012
Error bars represent mean standard error calculated from three biological replicates. Normalisation factors were calculated as the geometric mean of the expression levels of the three most stable reference genes (F-BOX, PP2A and L23) as determined by ...
Yongliang Zhang (122202)   +5 more
core   +1 more source

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