Results 151 to 160 of about 38,862 (256)

De Novo Design and Structural Optimization of Mn(salen)‐Based Artificial Metalloenzymes for Asymmetric Sulfoxidation

Angewandte Chemie, EarlyView.
We report the computational design of de novo proteins that bind Mn(salen)‐based complexes (L1) using Rosetta FastDesign and verified by AlphaFold2. After screening, the catalytic activity for the promising design (dnMSBP) toward enantioselective sulfoxidation of thioanisole was optimized based on its crystal structure. With 10 different substrates, we
Jing‐Xiang Wang, Yunling Deng, Indrek Kalvet, Amira Haque, Huiguang Dai, David Baker, Yi Lu   +6 more
wiley   +2 more sources

Multilevel Lumbar CT Attenuation Beyond L1: Comparison with QCT-Derived Volumetric Bone Mineral Density and Prevalent Fragility Fracture Status in a Diagnostic Referral Cohort. [PDF]

Diagnostics (Basel)
Andresen JR, Heisinger S, Haider T, Schober HC, Andresen R.   +4 more
europepmc   +1 more source

Transfer in L3 Acquisition: Is it Holistic or Property-Based? [PDF]

International Journal of Language & Linguistics, 2020
openaire   +1 more source

Intramolecular Nickel‐Catalyzed Reductive Coupling: Enantioselective Synthesis of Tetrahydroisoquinolines and Related Heterocycles

Angewandte Chemie, EarlyView.
The successful extension of the nickel‐catalyzed asymmetric coupling of polarized 1,3‐dienes with aldehydes to an intramolecular setting opens an efficient new entry into hydroxylated N‐heterocyclic compounds, most notably valuable tetrahydroisoquinolines.
Thilo Bender, Markus Leutzsch, Yannik Sell, Alois Fürstner   +3 more
wiley   +2 more sources

Computed Tomography-Derived Sarcopenia and Two- Versus Three-Dimensional Body Composition for Prognostication in Colorectal Cancer Patients Receiving Chemoradiotherapy: An Automated Deep Learning Segmentation Study with External Reproducibility Assessment. [PDF]

Healthcare (Basel)
Wang D, Sui J, Chen J, Chen L, Yang Q, Wang Y, Lin S.   +6 more
europepmc   +1 more source

Role of Graphene Oxide in the Nucleation and Growth of Gold Nanoparticles Revealed by Operando Time‐Resolved Studies

Angewandte Chemie, EarlyView.
Graphene oxide accelerates AuCl4− reduction under irradiation and directs edge‐selective nucleation and quasi‐one‐dimensional organization of gold nanoparticles at oxygen‐rich boundaries. Operando SAXS and UV–vis spectroscopy, supported by pulse radiolysis and DFT, reveal how progressive conversion of GO to rGO removes interfacial constraints, shifting
Liran Hu, Carine Clavaguéra, Zhenpeng Cui, Zhiwen Jiang, Thomas Bizien, Filippo Ferdeghini, Nguyen‐Thi Van‐Oanh, Michel Goldmann, François Muller, Samy Remita   +9 more
wiley   +2 more sources

Unusual Spinal Epidural and Paraspinal Venous Engorgement Secondary to Hepatosplenic Schistosomiasis: A Rare Cause of Severe Low Back Pain. [PDF]

Clin Case Rep
Birara ED, Bejiga YD, Girmaye R, Bayu EG, Anberber HM, Tadesse AA, Kidanu HF, Bayisa RG, Woyimo TG.   +8 more
europepmc   +1 more source

Atroposelective Pd(0)‐Catalyzed Direct Intermolecular C─H Arylation of Thiazole N‐Oxides Provides Access to Heterobiaryls

Angewandte Chemie, EarlyView.
An enantioselective Pd(0)‐catalysed arylation at the C4‐position of thiazole N‐oxides directly forges the atropochiral heterobiaryl axis. A tailored point‐ and axially chiral monodentate phosphine ensures high reactivities along with a tight stereocontrol.
Vitalii Smal, Nicolai Cramer
wiley   +2 more sources

An automated high-resolution screening platform identifies regulators of anchor cell invasion in <i>C. elegans</i>. [PDF]

Sci Adv
Berger S, Spiri S, Lattmann E, Engleitner S, Levesque MP, deMello A, Hajnal A.   +6 more
europepmc   +1 more source

Multilingual characteristics and cognition among older adults in India. [PDF]

Alzheimers Dement (Amst)
Arce Rentería M, Strangmann IM, Khobragade P, Snider MG, Petrosyan S, Narayanan S, Meijer E, Nichols E, Aksman LM, Lee J.   +9 more
europepmc   +1 more source