Results 121 to 130 of about 1,206 (138)
Long-term outcome of L86 and L97 protocols for adult acute lymphoblastic leukemia
Leukemia & Lymphoma, 2008 We analysed the long-term outcome of the L86 protocol using L-asparaginase (L-asp), vincristine (VCR) and prednisolone (PSL), collectively known as LVP or L97 protocol using LVP along with pirarubicin hydrochloride (THP-ADR) for 97 patients with acute lymphoblastic leukemia (ALL) diagnosed between 1986 and 2002.
Hideyuki, Koharazawa +15 more
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Flavopiridol (L86 8275; NSC 649890), a new kinase inhibitor for tumor therapy
International Journal of Oncology, 1996 Flavopiridol is a new synthetic flavone, structurally related to a natural alkaloid, originally purified from Dysoxylum binectariferum, a plant indigenous to India and used in Indian folk medicine. Flavopiridol was detected by a tandem screening system consisting in inhibition of the EGF-receptor Tyrosine phosphokinase and cytotoxicity. As a cytostatic
H, Sedlacek +10 more
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Application of Modified Flavone Closure for the Preparation of Racemic L86-8275
Organic Process Research & Development, 1999 The laboratory preparation of racemic L86-8275 (1a) and the salt (1b) is described in 7% overall yield. Our method eliminated a number of chromatography steps from the patent procedure and improved the flavone-forming reaction by employing a stepwise mechanism. Solvent-free conditions for the demethylation step are also described.
A. Christine Tabaka +3 more
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ChemInform, 1999 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A. Christine Tabaka +3 more
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J1349 Certified Power Engine Data for GM L86/L87 as used in 2019 T1xx - 93 Octane - Level 1
, 2023 This product includes information on the manufacturer, engine, application, testing location, certified maximum horsepower, certified maximum torque along with the certified curves of horsepower and torque over a wide range of engine RPM speeds.
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, 2023 This product includes information on the manufacturer, engine, applications, testing location, certified maximum horsepower, certified maximum torque along with the certified curves of horsepower and torque over a wide range of engine RPM speeds.
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, 2023 This product includes information on the manufacturer, engine, application, testing location, certified maximum horsepower, certified maximum torque along with the certified curves of horsepower and torque over a wide range of engine RPM speeds.
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Cancer Chemotherapy and Pharmacology, 1998 Flavopiridol is a flavone which inhibits several cyclin-dependent kinases, and exhibits potent growth-inhibitory activity against a number of human tumor cell lines both in vitro, and when grown as xenografts in mice. It is currently being evaluated in a phase I clinical trial at the National Cancer Institute.
S F, Stinson +4 more
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J1349 Certified Power Engine Data for GM L86/L87 as used in 2019 T1xx - 93 Octane - Level 2
, 2023 This product includes information on the manufacturer, engine, applications, testing location, certified maximum horsepower, certified maximum torque along with the certified curves of horsepower and torque over a wide range of engine RPM speeds.
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Cancer research, 1997 Flavopiridol, the first potent cyclin-dependent kinase inhibitor to undergo clinical trials as an antineoplastic agent in the United States, has attracted considerable attention because of its unique cellular targets and its ability to kill noncycling tumor cells in vitro.
K C, Bible, S H, Kaufmann
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