Results 31 to 40 of about 665 (114)

Efficacy of Der f 2/Zen 1‐LAMP1 Plasmid‐Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof‐of‐Concept Study

open access: yesVeterinary Dermatology, Volume 37, Issue 2, Page 306-318, April 2026.
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova   +6 more
wiley   +1 more source

Factor identification of intention to use cybernetic avatars using the extended UTAUT2 model

open access: yesComputers in Human Behavior Reports
As cybernetic avatar (CA) technology expands beyond extended reality (XR) settings into remote work, customer service, education, and healthcare, understanding its acceptance has become increasingly important, particularly in the post-COVID-19 era, as ...
Shinichi Yamaguchi   +5 more
doaj   +1 more source

Digital transformation, risk-taking, and innovation: Evidence from data on listed enterprises in China

open access: yesJournal of Innovation & Knowledge, 2023
This study uses text mining technology to construct an index of digital transformation and discusses the impact of digital transformation on enterprise innovation and its mechanisms from theoretical and empirical perspectives.
Meiyu Liu   +3 more
doaj   +1 more source

Activator of apoptosis harakiri (HRK) localisation at mitochondria alters mitochondrial morphology independently of other BCL‐2 proteins

open access: yesThe FEBS Journal, Volume 293, Issue 2, Page 549-564, January 2026.
How the structure of HRK, a member of the BCL‐2 protein family, contributes to its function is poorly understood. Functional analysis of HRK mutants reveals that HRK induces apoptosis in a BH3‐domain‐dependent, but transmembrane‐domain‐independent, manner. The transmembrane domain localises HRK to mitochondria, but alone is insufficient.
Louise E. King   +2 more
wiley   +1 more source

Impact of energy efficiency and sharing economy on the achievement of sustainable economic development: New evidences from China

open access: yesJournal of Innovation & Knowledge, 2023
Recently, energy efficiency and the sharing economy have become significant factors for sustainable economic development (SED), which require the attention of researchers and policymakers.
Fangyu Ye, Yi Li, Peilin Liu
doaj   +1 more source

Teleological Empathy: A Comprehensive Journey Through Its Conceptualization, Functional Characteristics, Ethical Challenges and Future Perspectives in the Contemporary Social Sciences

open access: yesAdvances in Human-Computer Interaction, Volume 2026, Issue 1, 2026.
The rapid proliferation of generative artificial intelligence and automated systems has radically transformed human interaction, introducing emerging forms of functional affective expression that profoundly challenge traditional biological definitions.
Félix Oscar Socorro Márquez   +2 more
wiley   +1 more source

Active Ageing Index, New Emphasis Within the Same Methodology. The Role of the Internet

open access: yesStudia Universitatis Vasile Goldis Arad, Seria Stiinte Economice, 2019
Our paper focuses on the role of the Internet in older people’s lives and suggests that the weighting given to Internet usage should be increased when calculating the Active Ageing Index (AAI).
Berde Éva, Kuncz Izabella
doaj   +1 more source

Characterization of Cytokine Treatment on Human Pancreatic Islets by Top‐Down Proteomics

open access: yesPROTEOMICS, Volume 25, Issue 24, Page 55-66, December 2025.
ABSTRACT Type 1 diabetes (T1D) results from autoimmune‐mediated destruction of insulin‐producing β cells in the pancreatic islet. This process is modulated by pro‐inflammatory cytokine signaling, which has been previously shown to alter protein expression in ex vivo islets.
Ashley N. Ives   +8 more
wiley   +1 more source

Exploration of natural products for the development of promising cholinesterase inhibitors in Alzheimer's disease treatment

open access: yesHeliyon
Cholinesterase enzymes (BuChE and AChE) are privileged biological targets for the symptomatic treatment of Alzheimer's disease. Indeed, inhibition of cholinesterase enzymes has been proven to improve the neurotransmission mechanisms in Alzheimer's ...
H. Nour   +5 more
semanticscholar   +1 more source

The Brand Image Influence on the Relationship Between Social Media Advertising and Sustainable Tourism Practices in Petra (Jordan)

open access: yesECONOMICS
This study aims to establish the mediating role of brand image, including advertising and promotion content distributed on social media platforms, which can improve positive brand image in the relationship between social media advertising and sustainable
Alfdool Sabri Mahmoud   +2 more
doaj   +1 more source

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