Results 41 to 50 of about 13,557 (179)

Characterization of Cytokine Treatment on Human Pancreatic Islets by Top‐Down Proteomics

PROTEOMICS, Volume 25, Issue 24, Page 55-66, December 2025.
ABSTRACT Type 1 diabetes (T1D) results from autoimmune‐mediated destruction of insulin‐producing β cells in the pancreatic islet. This process is modulated by pro‐inflammatory cytokine signaling, which has been previously shown to alter protein expression in ex vivo islets.
Ashley N. Ives, Tyler J. Sagendorf, Lorenz Nierves, Tai‐Tu Lin, Ercument Dirice, Rohit N. Kulkarni, Ljiljana Paša‐Tolić, Wei‐Jun Qian, James M. Fulcher   +8 more
wiley   +1 more source

Impact of energy efficiency and sharing economy on the achievement of sustainable economic development: New evidences from China

Journal of Innovation & Knowledge, 2023
Recently, energy efficiency and the sharing economy have become significant factors for sustainable economic development (SED), which require the attention of researchers and policymakers.
Fangyu Ye, Yi Li, Peilin Liu
doaj   +1 more source

The central engine of gamma-ray bursters [PDF]

, 1997
GRBs are thought to arise in relativistic blast-wave shocks at distances of 10 to 1000 AU from the point where the explosive energy is initially released.
Blandford R. D., M. Ruderman, Paczynski B., W. Kluźniak   +3 more
core   +3 more sources

An open‐label pilot study on an adsorbent mousse containing adelmidrol in client‐owned cats with feline atopic skin syndrome and associated seborrhoea

Veterinary Dermatology, Volume 36, Issue 5, Page 638-646, October 2025.
Background – Besides pruritus and skin lesions, cats with feline atopic skin syndrome (FASS) may have seborrhoea. Hypothesis/Objectives – The aim of this pilot study was to investigate whether an adsorbent mousse containing tapioca starch, adelmidrol and a nonpharmacological antimicrobial complex could decrease FASS‐associated seborrhoea in cats ...
Chiara Noli, Maria Federica Della Valle, Giada Morelli, Carlo Schievano, the Skinalia Clinical Research Group   +4 more
wiley   +1 more source

A Sectoral Perspective on the Sharing Economy’s Development

Folia Oeconomica Stetinensia
The sharing economy has experienced significant growth over the past decade. This phenomenon has introduced a new way of consuming services and goods. Nevertheless, while its benefits have been extensively studied, there is a limited understanding of its
Navickas Valentinas, Petrokė Ieva, Bilan Yuriy   +2 more
doaj   +1 more source

Effectiveness and treatment moderators of parenting interventions in Finnish perinatal primary care

Infant Mental Health Journal: Infancy and Early Childhood, Volume 46, Issue 5, Page 577-603, September 2025.
Abstract Perinatal parenting interventions may be important for enhancing parenting quality, but previous research has mostly focused on parental sensitivity. Other important outcomes, such as parental self‐efficacy (PSE), have rarely been studied. Research is also contradictory on whether parenting interventions can also enhance maternal mental health
Marjo Flykt, Markku Kilpeläinen, Susanne Kinnunen, Markus Salonen, Kirsi Peltonen, Sanna Isosävi, Jallu Lindblom   +6 more
wiley   +1 more source

Exploring Peptido‐Nanocomposites in the Context of Amyloid Diseases

Angewandte Chemie, Volume 136, Issue 9, February 26, 2024.
This review concerns the design principles, working mechanisms and application of peptido‐nanocomposites against amyloidosis, a hallmark of amyloid diseases. Abstract Therapeutic peptides are a major class of pharmaceutical drugs owing to their target‐binding specificity as well as their versatility in inhibiting aberrant protein‐protein interactions ...
Nicholas Andrikopoulos, Huayuan Tang, Yue Wang, Xiufang Liang, Yuhuan Li, Thomas P. Davis, Pu Chun Ke   +6 more
wiley   +2 more sources

Comparative Mass Spectroscopy Profiling of Masala Spices: Unveiling Direct and Remote Antimicrobial Effects of Nonvolatile and Aroma Metabolites via Biochemometric Tools and Molecular Networking

Food Frontiers, Volume 6, Issue 4, Page 1926-1953, July 2025.
Four major masala spices, Chaat, Pav Bhaji, Sambhar, and Tandoori, were analyzed using advanced multiplex mass spectrometry techniques. A total of 45 aroma compounds and 98 secondary metabolites were identified. These findings underscore the potential of masala spices not only as flavoring agents but also as potential food additives with antimicrobial ...
Mai E. Hussein, Mostafa H. Baky, Radwa H. El‐Akad, Mariam Hassan, Rupesh Deshmuk, Mohamed A. Farag   +5 more
wiley   +1 more source

Active Ageing Index, New Emphasis Within the Same Methodology. The Role of the Internet

Studia Universitatis Vasile Goldis Arad, Seria Stiinte Economice, 2019
Our paper focuses on the role of the Internet in older people’s lives and suggests that the weighting given to Internet usage should be increased when calculating the Active Ageing Index (AAI).
Berde Éva, Kuncz Izabella
doaj   +1 more source

Molecular characterization and structural basis of a promiscuous glycosyltransferase for β‐(1,6) oligoglucoside chain glycosides biosynthesis

Plant Biotechnology Journal, Volume 23, Issue 6, Page 2242-2253, June 2025.
We highlight a novel multi‐step O‐glycosyltransferase, UGT94BY1, which exhibits high promiscuity toward triterpene saponins and flavonoid glycosides for the formation of β‐(1,6) oligoglucoside chains. Through crystal structure analysis and theoretical calculations, we uncovered the mechanisms underlying substrate promiscuity and sugar chain extension ...
Zhennan Jiang, Nianhang Chen, Hao‐Tian Wang, Yungang Tian, Xiaoyu Du, Ruibo Wu, Luqi Huang, Zi‐Long Wang, Yuan Yuan   +8 more
wiley   +1 more source