Results 21 to 30 of about 587 (132)

A escuta analítica como instrumento de resgate e manutenção do laço social

Estudos Interdisciplinares em Psicologia, 2020
O presente trabalho é fruto do projeto “Jovens em situação de vulnerabilidade social: entre o trauma e o reconhecimento” desenvolvido com bolsa de iniciação científica concedida pela FAPERJ.
Maria Manuela Dias Ramos de Macedo, Perla Klautau   +1 more
doaj   +1 more source

Interaction Between Rec8 and Mis4 Is Required for Axis‐Loop Chromatin Formation and Homologous Chromosome Recombination During Meiosis

Genes to Cells, Volume 31, Issue 4, July 2026.
We identified a Mis4 cohesin loader mutant that is specifically defective in chromatin axis formation and homologous recombination while retaining normal sister chromatid cohesion. The mis4‐LR mutant, carrying the L1150S and R1159G amino acid substitutions, exhibited reduced interaction between Mis4 and Rec8, suggesting a meiosis‐specific role for the ...
Takeshi Sakuno, Yasuto Murayama, Tokuko Haraguchi, Yasushi Hiraoka   +3 more
wiley   +1 more source

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, Volume 38, Issue 34, 17 June 2026.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source

Approaching Sixfold Chemical Bonding: Metal Dimers MM' Involving Group 4–8 Transition Metals and the Actinides Th–Np. Additive Covalent Radii r6$r_6$

Chemistry – A European Journal, Volume 32, Issue 18, 14 May 2026.
Twelve‐valence‐electron transition metal dimers MM', like diatomic Mo2, can have nearly sixfold bonds. Values of r6$r_6$ for over 20 elements from Sc to Pu are proposed. ABSTRACT A set of additive covalent radii is fitted to a combination of experimental data, accurate ab initio computations, and more approximate DFT MM' bond lengths, R$R$, with 12 ...
Pekka Pyykkö, Michiko Atsumi
wiley   +1 more source

Less Genome, More Gain: Genome Reduction Enhances Transaminase‐Producing E. coli in a Scale‐Down Bioreactor

Engineering in Life Sciences, Volume 26, Issue 4, April 2026.
ABSTRACT In large‐scale bioprocesses, mixing limitations and design constraints cause the onset of heterogeneous environments, subjecting the cells to continuously changing external conditions, often reducing their performance compared to laboratory conditions.
Gennaro Avolio, Simon Klaffl, Ralf Takors   +2 more
wiley   +1 more source

A adolescência generalizada como efeito do discurso do capitalista e da adultez erodida [PDF]

Psicologia & Sociedade, 2014
A noção de que vivemos em tempos de adolescência generalizada coloca em questão tanto o que diz respeito a formas contemporâneas do laço social quanto o conceito de adolescência em psicanálise para interpretá-las.
Marcelo Ricardo Pereira, Rose Gurski
doaj   +3 more sources

From 0D to 3D: Structural Design of Metal‐Organic Framework‐Derived Composites for Next‐Generation Microwave Absorption

Small Structures, Volume 7, Issue 4, April 2026.
This review establishes a dimensional engineering paradigm for MOF‐derived absorbers, transitioning from discrete 0D units to 3D composite architectures. It highlights dimension–structure–performance correlations and provides insights into data‐driven and sustainable design for future high‐efficiency microwave absorption, aiming to guide the ...
Wangsheng Lai, Jun Li, Lulu Zou, Yihan Zhu, Haomin Yin, Xiangyun Huang, Juan Wang, Cong Yi, Fangzhou Pan, Junjie Yan, Lin Xiao, Wenfeng Wang, Jiaxun Hu, Mei Wu, Qikui Man, Guoguo Tan, Xiao Chi   +16 more
wiley   +1 more source

O que resta da adolescência

Estilos da Clínica, 2020
Os processos dos adolescentes diante dos dilemas humanos relativos à sexualidade, morte, pertença e transformação social contam a sua própria história, mas dizem também sobre o modo como cada sociedade concebe as modalidades de inscrição do sujeito no ...
Miriam Debieux Rosa, Viviani Carmo-Huerta   +1 more
doaj   +1 more source

Folate receptor alpha (FRα) expression in tubo‐ovarian and endometrial tumors: a study of 923 cases

The Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.
Abstract Folate receptor alpha (FRα) is a promising therapeutic target due to its high expression in several tumor types and its rare expression in healthy tissue. Recently, the antibody‐drug conjugate mirvetuximab soravtansine has been approved for treatment of advanced platinum‐resistant high‐grade serous carcinoma (HGSC).
Isabela Töltési, Kristýna Němejcová, Michaela Kendall Bártů, Romana Vránková, David Cibula, Pavel Fabian, Filip Frühauf, Jitka Hausnerová, Jan Laco, Gábor Méhes, Zuzana Špůrková, Marián Švajdler, Radoslav Matěj, Pavel Dundr   +13 more
wiley   +1 more source

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

Advanced Science, Volume 13, Issue 12, 27 February 2026.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo, Dongwon Park, Woosub Shin, Jongmin Kim   +3 more
wiley   +1 more source