Results 131 to 140 of about 35,489,065 (303)

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

Chemically Gradient Ordered Nanodomains Enable Large Tensile Ductility in Gigapascal Lightweight Refractory High‐Entropy Alloys

Advanced Science, EarlyView.
A high‐strength lightweight refractory high‐entropy alloy achieves extraordinary ductility owing to the introduction of coherent chemically gradient ordered nanodomains (CGONs). The CGONs not only serve as effective barriers to dislocation motion (strengthening) but also significantly promote dislocation nucleation and multiplication (ductilizing) upon
Wei Zhang, Dingshun Yan, Yong Zhang, Zhiming Li   +3 more
wiley   +1 more source

Standardless LA-ICP-MS fission-track dating in apatite: comparison with uranium thin film and LA-ICP-MS ζ-calibration

Abstract Over the past two decades, the fission-track community has sought to calibrate the ages with LA-ICP-MS. This technique has not only made thermochronology faster but also enabled the determination of U-Pb ages and the measurements of trace elements which support geological interpretation.
Cleber J. Soares, Julio C. Hadler, Sandro Guedes, Luca Caracciolo, Leonardo B. L. Lopes   +4 more
openaire   +1 more source

Tackling the Challenging Determination of Trace Elements in Ultrapure Silicon Carbide by LA-ICP-MS. [PDF]

Molecules, 2023
Spanu D, Palestra A, Prina V, Monticelli D, Bonanomi S, Nanot SU, Binda G, Rampazzi L, Sessa G, Callejo Munoz D, Recchia S.   +10 more
europepmc   +1 more source

In Situ Reconstructed Crystalline–Amorphous CuNi Nanotubes Unifying Activity and Stability for Oxygen Evolution

Advanced Science, EarlyView.
Controlled electrochemical reconstruction creates a crystalline–amorphous CuNi nanotube that unifies catalytic activity and durability for alkaline oxygen evolution. The conductive metallic core and active amorphous oxide shell work synergistically to deliver low overpotential and exceptional stability exceeding 1000 h, offering a new strategy for ...
Shi‐Yu Zhu, Han Gao, Meng Li, Ling‐Rui Wang, Tian‐Yu Xia, Wei‐Di Liu, Xiao‐Lei Shi, Hai‐Zhong Guo, Zhi‐Gang Chen   +8 more
wiley   +1 more source

Time-of-flight ICP-MS laser ablation zircon geochronology: Assessment and comparison against quadrupole ICP-MS

, 2020
This study presents U–Pb isotopic results from the mineral zircon measured by nanosecond laser ablation coupled to either a time-of-flight inductively coupled plasma mass spectrometer (ICP-MS), a quadrupole ICP-MS or both via a split stream arrangement ...
Thompson, JM (15564395), Borovinskaya, O (15727697), Leonid Danyushevsky (14734807), Tanner, M (15532904)   +3 more
core  

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

A comparative study of five reference materials and the Lombard meteorite for the determination of the platinum-group elements and gold by LA-ICP-MS

, 2013
A range of independently characterised reference materials (RMs) for LA-ICP-MS, used for the determination of the platinum-group elements (PGE) and Au in a sulfide matrix, were analysed and compared: 8b, PGE-A, NiS-3, Po727-T1, Po724-T and the Lombard ...
Philip Robinson (14748139), Wohlgemuth-Ueberwasser, C (15579809), Savard, D (15579815), Pearson, N (15579812), Gilbert, S (15534821), Hanley, J (15579818), Norman, M (15551522), Leonid Danyushevsky (14734807)   +7 more
core  

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Assessing data reliability for AI-driven volcanic rock dating: A comparison of electron microprobe and laser ablation mass spectroscopy

Applied Computing and Geosciences
This study explores the integrationof artificial intelligence (AI) and modern data analytics for accurately predicting and classifying three distinct periods of volcanic activity.
Ali Salimian, Megan Watfa, Ram Grung, Lorna Anguilano   +3 more
doaj   +1 more source