Results 21 to 30 of about 9,862 (201)

Segmental composition and nerve distribution of the brachial plexus in Galictis cuja

The Anatomical Record, EarlyView.
Abstract Galictis cuja is a neotropical mustelid with terrestrial locomotor habits, yet the anatomy of its brachial plexus has remained undescribed. This study characterizes the origin, organization, and distribution of the brachial plexus nerves in 15 adult specimens (30 antimeres).
Natan da Cruz de Carvalho, Thais Mattos Estruc, Ingrid Bete Palmeira, Julia Fagundes Franco, Emillin Reis Bermudez, Paulo de Souza‐Junior, Marcelo Abidu‐Figueiredo   +6 more
wiley   +1 more source

Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib

Clinical Pharmacology &Therapeutics, EarlyView.
Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi, Mwila Mulubwa, Mmakwena M. Mmonwa, Mathew Njoroge, Liezl Krugmann, Kelly Chibale   +5 more
wiley   +1 more source

Tau-PET correlates of mild behavioral impairment in preclinical and prodromal Alzheimer's disease: A head-to-head comparison of Flortaucipir and MK6240. [PDF]

Alzheimers Dement
Abstract INTRODUCTION We compared the association between mild behavioral impairment (MBI) and first‐ versus second‐generation tau‐positron emission tomography (PET) tracers in preclinical and prodromal Alzheimer's disease (AD). METHODS We assessed 110 individuals with head‐to‐head [18F]MK6240 and [18F]Flortaucipir tau‐PET.
Bizzi I, Macedo AC, Trudel L, Therriault J, Rahmouni N, Lussier FZ, Tissot C, Bezgin G, Aumont É, Chan T, Hosseini SA, Oliva-Lopez D, Gonçalves MP, Povala G, Ferreira PCL, Bellaver B, Amaral L, Ruppert E, Medeiros MS, Mroué R, Rocha A, Ng KP, Zimmer ER, Masdeu J, Pascual B, Lowe VJ, Oh H, Soleimani-Meigooni DN, Fortea J, Ismail Z, Baker S, Pascoal TA, Rosa-Neto P, HEAD Study.   +33 more
europepmc   +2 more sources

Configuration of the economic structure of La Pampa

Perspectivas, 2020
The aim of this article is to define conceptually and quantitatively the economic structure of La Pampa. The scope of this research covers general characteristics of its territory, population and production, opening it in primary, secondary and tertiary production, and its consequent exports.
openaire   +1 more source

Phytochemistry, Chemotypic Diversity and Antimicrobial Potential of Essential Oils From Native Aromatic Plants of the Americas: A Systematic Review

Flavour and Fragrance Journal, EarlyView.
This review bridges ancestral indigenous knowledge with modern pharmacology, summarizing the phytochemistry and antimicrobial properties of essential oils from seven native American species. It highlights their significant activity against bacterial, fungal and parasitic pathogens, emphasizing their potential as sustainable therapeutic and agricultural
Arley Rey Páez, Mozaniel Santana de Oliveira, João Paulo Viana Leite   +2 more
wiley   +1 more source

Machine Learning‐Based Correction of Reanalysis Surface Radiation Fluxes Using Ground‐Measured Data in the Southern Brazilian Pampa Biome

International Journal of Climatology, EarlyView.
This study demonstrates that ERA5 provides more accurate surface radiation flux estimates than MERRA2 across the Southern Brazilian Pampa. Machine learning models, particularly Random Forest, further improved the precision of reanalysis data for climate applications.
Olusola Samuel Ojo, Michel Baptistella Stefanello, Alecsander Mergen, Maria Eduarda Oliveira Pinheiro, Vanessa de Arruda Souza, Débora Regina Roberti   +5 more
wiley   +1 more source

Estudio comparativo de la densidad del complejo de orugas cortadoras en diferentes ambientes y cultivos antecesores

Semiárida, 2018
Con el objetivo de conocer si el cultivo antecesor y el ambiente dentro del lote inciden en la densidad de las larvas presentes en el momento de la siembra de los cultivos de verano, a mediados de septiembre de 2014, se realizó un estudio en el ...
Andrés Corro Molas, Estela Baudino, Juliana Vilches, Walter Guillot Giraudo, Emiliano Capozzi, Selene Niveyro, Carlos Ferrero, Agustín Civalero   +7 more
doaj  

Bromelain as the enzyme of the future: A global bibliometric mapping of its applications and emerging trends

Journal of the Science of Food and Agriculture, EarlyView.
Abstract INTRODUCTION Bromelain, a complex mixture of proteolytic enzymes primarily extracted from plants of the Bromeliaceae family, has gained prominence because of its broad industrial applicability, particularly in the food, pharmaceutical and cosmetic sectors.
Genésio José da Silva Neto, Tonny Cley Campos Leite, Mônica Tejo Cavalcanti, Geany Targino Sousa Pedrosa, Rerisson do Nascimento Alves, Amanda Reges de Sena, Mônica Correia Gonçalves   +6 more
wiley   +1 more source

Estudios en plantas arvenses/malezas de la región pampeana central: ecología y manejo

Semiárida, 2018
Tanto la superficie como el rendimiento de los cultivos extensivos siguen su marcha ascendente en la actualidad, con un fuerte predominio de soja y otras oleaginosas y con una clara tendencia al aumento y a la difusión de cultivos genéticamente ...
Carla Etel Suárez, Jorgelina Montoya, Carolina Porfiri, Juan Manuel Cervellini, Héctor Daniel Estelrich, Fernando Porta Siota, Anibal Oscar Prina, Ernesto Atilio Morici   +7 more
doaj  

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source