Results 241 to 250 of about 35,329,736 (299)

Limiting Trial‐and‐Error: Linker‐Based 2D Descriptor Analysis to Support Very Early Proteolysis‐Targeting Chimeras Design

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
Can simple linker descriptors guide PROTAC design? Analysis of matched CRBN‐ and VHL‐recruiting degraders shows that basic 2D linker properties may capture trends linked to degradation efficiency, in vitro ADME and physicochemical properties. A practical approach to reduce trial‐and‐error in early targeted protein degradation programs. Targeted protein
Giulia Apprato, Serena Traversa, Giulia Caron, Giuseppe Ermondi   +3 more
wiley   +1 more source

[A rare combination of relapsing polychondritis and systemic lupus erythematosus: a case report]. [PDF]

Pan Afr Med J
Ndong VS, Taki G, Harmouche H.
europepmc   +1 more source

The KRAS targeting revolution in metastatic pancreatic cancer: insights from the landmark RASolute-302 trial and emerging allele-specific strategies at ASCO 2026. [PDF]

J Hematol Oncol
Pillozzi S, Giommoni E, Petroni G, Rossini D, Lavacchi D, Brugia M, Galli A, Antonuzzo L.   +7 more
europepmc   +1 more source

Immobilization of the Proteolytic Fraction P1G10 from <i>Vasconcellea pubescens</i> in Alginate-Chitosan Complex and Enzyme Activity Release. [PDF]

Molecules
Cisternas-Jamet J, Plaza V, Salas C, Bernal C, Castillo L.   +4 more
europepmc   +1 more source

<i>ESR1</i> mutations in ER-positive breast cancer: from endocrine resistance to ctDNA-guided therapeutic interception. [PDF]

Explor Target Antitumor Ther
Martinez T, Wegner S, Bahmad HF.
europepmc   +1 more source

Archidiócesis de La Serena

Enciclopedia Católica
core  

Management of the Clinically N0 Neck in Maxillary Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis. [PDF]

J Clin Med
Maglitto F, Salzano G, Trotta S, Manzo E, Vaira LA, Committeri U, Troise S, Dell'Aversana Orabona G.   +7 more
europepmc   +1 more source

Multidisciplinary approach and rehabilitation practice for defecatory disorders in Italy: a snapshot survey on behalf of the Italian Society of Colorectal Surgery (SICCR). [PDF]

Tech Coloproctol
Zigiotto D, La Greca G, Elio A, Santoro GA, Orlandi S, Pelvic Floor Rehabilitation Group.   +5 more
europepmc   +1 more source

Identifying the angiogenic receptor expression in mantle cell lymphoma patients and murine models. [PDF]

Biomark Res
Singh S, Wang Y, Sircar A, Jindal U, Srour N, La Ferlita A, Distefano R, Soni A, Kumar D, Peralta-Camacho GJ, Zhao SL, Jafari H, Holter JC, Tinapple JW, Barlage JM, Kumar R, Berger M, Rahman K, Nezati R, Nath UK, Chaudhary N, Ranganathan P, Muthusamy N, Amador V, Li PK, Parekh S, Paik J, Baiocchi R, Song JW, Alinari L, Peterson BR, Epperla N, Jain N, Sehgal L.   +33 more
europepmc   +1 more source

Determinants of Non-infectious Scleritis Complications and Their Impact on Visual Outcome: Results from the International AIDA Network Scleritis Registry. [PDF]

Ophthalmol Ther
Sota J, Hinojosa-Azaola A, de-la-Torre A, Giardini HAM, Guerriero S, Kawakami-Campos PA, Martín-Nares E, Guaracha-Basañez GA, Ragab G, Chimenti MS, Lopalco G, Hissaria P, Cattalini M, Ruscitti P, Tharwat S, Ruiz-Irastorza G, García-Madero JJ, Tierradentro-Alape R, Hegazy MT, Afifi K, Emmi G, Parronchi P, Paroli MP, Hernández-Rodríguez J, Sainz-de-la-Maza M, Caggiano V, Sbalchiero J, Bugatti S, Gaggiano C, Breda L, Dammacco R, Monosi B, Capodiferro M, Beecher M, Olivieri AN, Batu ED, Ozen S, Frediani B, Thabet M, Balistreri A, Gupta V, Fonollosa A, Vitale A, Cantarini L, Fabiani C, Study Group of Systemic Autoinflammatory Disease of SIR (Italian Society of Rheumatology).   +45 more
europepmc   +1 more source