Results 101 to 110 of about 127,832,786 (299)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Lab-on-a-chip devices for global health: Past studies and future opportunities
A rapidly emerging field in lab-on-a-chip (LOC) research is the development of devices to improve the health of people in developing countries. In this review, we identify diseases that are most in need of new health technologies, discuss special design ...
Chin, C. D., Sia, S. K., Linder, V.
core +1 more source
Acoustically Actuated Flow in Microrobots Powered by Axisymmetric Resonant Bubbles
Advanced Intelligent SystemsBubble‐driven microsystems inspired by the therapeutic use of microbubbles under clinical ultrasound actuation offer innovative remote manipulation in biological settings.
Sumit Mohanty +5 more
doaj +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
3D printed nervous system on a chip
, 2015 Bioinspired organ-level in vitro platforms are emerging as effective technologies for fundamental research, drug discovery, and personalized healthcare. In particular, models for nervous system research are especially important, due to the complexity of ...
Meng, Fanben +6 more
core +1 more source
Nanophotonic lab-on-a-chip platforms including novel bimodal interferometers, microfluidics and grating couplers [PDF]
, 2012 One of the main limitations for achieving truly lab-on-a-chip (LOC) devices for point-of-care diagnosis is the incorporation of the "on-chip" detection.
Lechuga, Laura M +8 more
core +1 more source
Nanotechnology Reviews, 2014 Lab-on-a-chip (LOC) systems are extensively used in recent times for applications in nanotechnology ranging from synthesis of nanomaterials to their utilization in catalysis, biomedicine, and drug delivery.
Navin Chelliah V. +3 more
doaj +1 more source
Biomedical Engineering Letters, 2012 Biological and medical applications of lab a on a chip is a timely topic that is active area of research worldwide. Biomedical Engineering Letters is well positioned to contribute to reporting important results in this area. The field is continually evolving as lab on chip technologies and associated fabrication methods mature and the focus of research
openaire +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Ultrasound assisted particle and cell manipulation on-chip [PDF]
, 2013 Ultrasonic fields are able to exert forces on cells and other micron-scale particles, including microbubbles. The technology is compatible with existing lab-on-chip techniques and is complementary to many alternative manipulation approaches due to its ...
Cochran, Sandy +2 more
core +1 more source