Results 121 to 130 of about 127,832,786 (299)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

On-chip immuno-agglutination assay with analyte capture by dynamic manipulation of superparamagnetic beads

Magnetic bead-based lab-on-a-chip systems offer significant advantages compared to more conventional systems, mainly through the possibility of controlled manipulation of the magnetic carriers on-chip.
Moser, Yves, Thomas, Lehnert, Gijs, Martin   +2 more
core   +1 more source

High-throughput quantitative imaging of cell spreading dynamics by multi-step microscopy projection photolithography based on a cell- friendly photoresist

, 2018
A new method for the high-throughput study of cell spreading dynamics is devised by multi-step microscopy projection photolithography based on a cell-friendly photoresist.
jong-cheol choi, Doh, J
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Accelerated Computational Fluid Dynamics Simulations of Microfluidic Devices by Exploiting Higher Levels of Abstraction

Micromachines
The design of microfluidic devices is a cumbersome and tedious process that can be significantly improved by simulation. Methods based on Computational Fluid Dynamics (CFD) are considered state-of-the-art, but require extensive compute time—oftentimes ...
Michel Takken, Robert Wille
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Lab-on-a-chip : a component view

, 2010
Miniaturization is being increasingly applied to biological and chemical analysis processes. Lab-on-a-chip systems are direct creation of the advancement in the miniaturization of these processes.
Abbas Kouzani (13079637), Wei Duan (13099662), Yang Lim (13100577)   +2 more
core  

Sample solution constraints on motor-driven diagnostic nanodevices

, 2013
The last decade has seen appreciable advancements in efforts towards increased portability of lab-on-a-chip devices by substituting microfluidics with molecular motor-based transportation. As of now, first proof-of-principle devices have analyzed protein
Albet-Torres, Nuria,, Månsson, Alf,, te Kronnie, Geertruy, Korten, Till, Månsson, Alf, Korten, Slobodanka, Paderi, Francesca, ten Siethoff, Lasse,, Diez, Stefan, Albet-Torres, Nuria   +9 more
core   +1 more source

Microfluidic technologies: from fundamental principles to advanced fabrication and applications

AAPS Open
Conventional drug delivery systems, model study systems, drug analysis systems and drug interactions systems have been in use since ages. But these conventional methods struggle with significant limitations like lack of precise targeting, irregular ...
Rupam Deka, Shrutie Shivam, Debarupa Dutta Chakraborty, Prithviraj Chakraborty   +3 more
doaj   +1 more source