Results 1 to 10 of about 94,583 (304)

Lab-on-a-chip or Chip-in-a-lab: Challenges of Commercialization Lost in Translation

Procedia Technology, 2015
AbstractLab-on-a-chip technology has been long envisaged to have tremendous commercial potential, owing to the ability of such devices to encapsulate a full range of laboratory processes in a single instrument and operate in a portable manner, rapidly and at low cost.
Mazher Iqbal Mohammed, Ian Gibson
exaly   +3 more sources

Organ-on-a-Chip and Lab-on-a-Chip Technologies in Cardiac Tissue Engineering [PDF]

Biomimetics
Microfluidic technologies have ushered in a new era in cardiac tissue engineering, providing more predictive in vitro models compared to two-dimensional culture studies. This review examines Organ-on-a-Chip (OoC) and Lab-on-a-Chip (LoC) platforms, with a
Daniele Marazzi, Federica Trovalusci, Paolo Di Nardo, Felicia Carotenuto   +3 more
doaj   +2 more sources

Droplet microreactor for high-throughput fluorescence-based measurements of single catalyst particle acidity

Microsystems & Nanoengineering, 2023
The particles of heterogeneous catalysts differ greatly in size, morphology, and most importantly, in activity. Studying these catalyst particles in batch typically results in ensemble averages, without any information at the level of individual catalyst
Jeroen C. Vollenbroek, Anne-Eva Nieuwelink, Johan G. Bomer, Roald M. Tiggelaar, Albert van den Berg, Bert M. Weckhuysen, Mathieu Odijk   +6 more
doaj   +1 more source

Label-Free Microfluidic Impedance Cytometry for Acrosome Integrity Assessment of Boar Spermatozoa

Biosensors, 2022
Microfluidics and lab-on-chip technologies have been used in a wide range of biomedical applications. They are known as versatile, rapid, and low-cost alternatives for expensive equipment and time-intensive processing.
Stella A. Kruit, Douwe S. de Bruijn, Marleen L. W. J. Broekhuijse, Wouter Olthuis, Loes I. Segerink   +4 more
doaj   +1 more source

Systematic characterization of cleanroom-free fabricated macrovalves, demonstrating pumps and mixers for automated fluid handling tuned for organ-on-chip applications

Microsystems & Nanoengineering, 2022
Integrated valves enable automated control in microfluidic systems, as they can be applied for mixing, pumping and compartmentalization purposes. Such automation would be highly valuable for applications in organ-on-chip (OoC) systems.
Elsbeth G. B. M. Bossink, Anke R. Vollertsen, Joshua T. Loessberg-Zahl, Andries D. van der Meer, Loes I. Segerink, Mathieu Odijk   +5 more
doaj   +1 more source

Determining Particle Size and Position in a Coplanar Electrode Setup Using Measured Opacity for Microfluidic Cytometry

Biosensors, 2021
Microfluidic impedance flow cytometers enable high-throughput, non-invasive, and label-free detection of single-cells. Cytometers with coplanar electrodes are easy and cheap to fabricate, but are sensitive to positional differences of passing particles ...
Douwe S. de Bruijn, Koen F. A. Jorissen, Wouter Olthuis, Albert van den Berg   +3 more
doaj   +1 more source

Determining the antioxidant properties of various beverages using staircase voltammetry

Heliyon, 2020
Antioxidants are molecules that neutralize reactive oxygen species in the human body, reportedly reducing the risk of cancer and cardiovascular diseases. With multiple dietary products being advertised by their assumed high antioxidant concentration, the
W.H. Schilder, E. Tanumihardja, A.M. Leferink, A. van den Berg, W. Olthuis   +4 more
doaj   +1 more source

From chip-in-a-lab to lab-on-a-chip: a portable Coulter counter using a modular platform [PDF]

Microsystems & Nanoengineering, 2018
AbstractThe field of microfluidics has been struggling to obtain widespread market penetration. In order to overcome this struggle, a standardized and modular platform is introduced and applied. By providing easy-to-fabricate modular building blocks which are compatible with mass manufacturing, we decrease the gap from lab-to-fab.
Stefan Dekker, Pelin Kubra Isgor, Tobias Feijten, Loes I. Segerink, Mathieu Odijk   +4 more
openaire   +3 more sources

Patterning Biological Gels for 3D Cell Culture inside Microfluidic Devices by Local Surface Modification through Laminar Flow Patterning

Micromachines, 2020
Microfluidic devices are used extensively in the development of new in vitro cell culture models like organs-on-chips. A typical feature of such devices is the patterning of biological hydrogels to offer cultured cells and tissues a controlled three ...
Joshua Loessberg-Zahl, Jelle Beumer, Albert van den Berg, Jan C. T. Eijkel, Andries D. van der Meer   +4 more
doaj   +1 more source

A lab-on-a-chip model of glaucoma [PDF]

Brain and Behavior, 2019
Abstract We developed a glaucoma-on-a-chip (GOC) model to evaluate the viability of retinal ganglion cells (RGCs) against high pressure and the potential effect of neuroprotection. A three-layered chip consisting of interconnecting microchannels and culture wells was designed based on simulation of physical parameters.
Nafian, Fatemeh, Azad, Babak Kamali Doust, Yazdani, Shahin, Rasaee, Mohammad Javad, Daftarian, Narsis   +4 more
openaire   +3 more sources