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Phospholipid Polymer Biointerfaces for Lab-on-a-Chip Devices

Annals of Biomedical Engineering, 2010
This review summarizes recent achievements and progress in the development of various functional 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer biointerfaces for lab-on-a-chip devices and applications. As phospholipid polymers, MPC polymers can form cell-membrane-like surfaces by surface chemistry and physics and thereby provide biointerfaces ...
Yan, Xu   +2 more
openaire   +2 more sources

Chitosan: an integrative biomaterial for lab-on-a-chip devices

Lab on a Chip, 2010
Chitosan is a naturally derived polymer with applications in a variety of industrial and biomedical fields. Recently, it has emerged as a promising material for biological functionalization of microelectromechanical systems (bioMEMS). Due to its unique chemical properties and film forming ability, chitosan serves as a matrix for the assembly of ...
S T, Koev   +6 more
openaire   +2 more sources

Lab-on-a-Chip Devices for Chemical Analysis

2013
[Excerpt] Overview: The healthcare sector is nowadays one of the most dynamic and where novelty is a strategic and operational imperative. The possibility of increasing the quantity and quality of clinical analyses, performed with instantaneous results and outside clinical laboratories, contributes to a better quality in healthcare services and also a ...
Minas, Graça, Catarino, Susana Oliveira
openaire   +2 more sources

Lab-on-a-Chip Devices for Chemical Analysis

2008
A Lab-on-a-Chip for chemical analysis is a miniaturized device capable of analyzing chemical parameters in fluids. It comprises in a single chip the liquid-handling, the detection and the readout systems. Its reduced size and weight could improve the performance of an analysis and allow the device to be used in mobile chemical analysis equipment, such ...
openaire   +2 more sources

“Lab-on-a-Chip” Devices for Cellular Arrays Based on Dielectrophoresis

2007
Dielectrophoresis (DEP)-based lab-on-a-chip devices represent a very appealing approach for cell manipulation and will enable laboratory testing to move from laboratories into nonlaboratory settings. DEP-based lab-on-a-chip platforms involve the miniaturization of several complex chemical and physical procedures in a single microchip-based device ...
GAMBARI, Roberto   +12 more
openaire   +3 more sources

Design and Simulation of Lab-on-a-Chip Devices

2014
Microfluidic channels are an essential part of any lab-on-a-chip system. They usually perform various functions, such as transporting liquids from A to B or mixing or separating liquids. As production costs for such systems are not insignificant, it is essential that the systems are designed properly before the fabrication, in order to avoid ...
Maria Dimaki, Fridolin Okkels
openaire   +1 more source

Multiplexed optical pathogen detection with lab‐on‐a‐chip devices

Journal of Biophotonics, 2009
AbstractInfectious diseases are still a main cause of human morbidity and mortality. Advanced diagnostics is considered to be a key driver to improve the respective therapeutic outcome. The main factors influencing the impact of diagnostics include: assay speed, availability, information content, in‐vitro diagnostics and cost, for which molecular ...
Holger, Schulze   +3 more
openaire   +2 more sources

Integrated electrochemical DNA biosensors for lab‐on‐a‐chip devices

ELECTROPHORESIS, 2009
AbstractAnalytical devices able to perform accurate and fast automatic DNA detection or sequencing procedures have many potential benefits in the biomedical and environmental fields. The conversion of biological or biochemical responses into quantifiable optical, mechanical or electronic signals is achieved by means of biosensors.
Mònica, Mir   +2 more
openaire   +2 more sources

Development of a lab-on-a-chip device for diagnosis of plant pathogens

Biosensors and Bioelectronics, 2011
A lab-on-a-chip system for rapid nucleic acid-based analysis was developed that can be applied for diagnosis of selected Phytophthora species as a first example for use in plant pathology. All necessary polymerase chain reaction process (PCR) and hybridization steps can be performed consecutively within a single chip consisting of two components, an ...
Sandra, Julich   +9 more
openaire   +2 more sources

Smart devices: lab-on-a-chip

2017
Microfluidic devices have become a reality in the healthcare sector for the analysis of (bio) chemical parameters and diagnosis applications, due to their small dimensions, accuracy, low cost, low power consumption, and portability. This chapter intends to discuss the main challenges regarding the application of lab-on-a-chip devices for diagnosis ...
Catarino, Susana Oliveira   +2 more
openaire   +1 more source

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