Results 261 to 270 of about 1,130,940 (308)
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Multiplexed optical pathogen detection with lab‐on‐a‐chip devices
Journal of Biophotonics, 2009AbstractInfectious diseases are still a main cause of human morbidity and mortality. Advanced diagnostics is considered to be a key driver to improve the respective therapeutic outcome. The main factors influencing the impact of diagnostics include: assay speed, availability, information content, in‐vitro diagnostics and cost, for which molecular ...
Holger, Schulze +3 more
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Integrated electrochemical DNA biosensors for lab‐on‐a‐chip devices
ELECTROPHORESIS, 2009AbstractAnalytical devices able to perform accurate and fast automatic DNA detection or sequencing procedures have many potential benefits in the biomedical and environmental fields. The conversion of biological or biochemical responses into quantifiable optical, mechanical or electronic signals is achieved by means of biosensors.
Mònica, Mir +2 more
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Development of a lab-on-a-chip device for diagnosis of plant pathogens
Biosensors and Bioelectronics, 2011A lab-on-a-chip system for rapid nucleic acid-based analysis was developed that can be applied for diagnosis of selected Phytophthora species as a first example for use in plant pathology. All necessary polymerase chain reaction process (PCR) and hybridization steps can be performed consecutively within a single chip consisting of two components, an ...
Sandra, Julich +9 more
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2017
Microfluidic devices have become a reality in the healthcare sector for the analysis of (bio) chemical parameters and diagnosis applications, due to their small dimensions, accuracy, low cost, low power consumption, and portability. This chapter intends to discuss the main challenges regarding the application of lab-on-a-chip devices for diagnosis ...
Catarino, Susana Oliveira +2 more
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Microfluidic devices have become a reality in the healthcare sector for the analysis of (bio) chemical parameters and diagnosis applications, due to their small dimensions, accuracy, low cost, low power consumption, and portability. This chapter intends to discuss the main challenges regarding the application of lab-on-a-chip devices for diagnosis ...
Catarino, Susana Oliveira +2 more
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Silicon nanophotonic devices for integrated lab-on-a-chip sensing
2010 Annual International Conference of the IEEE Engineering in Medicine and Biology, 2010We present our recent progress in designing nanophotonic devices for integrated sensing applications. We focus on Si-based microresonators and on-chip spectrometers as the main building blocks to implement compact sensing platforms with strong light-matter interaction.
Babak, Momeni +5 more
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Single cells as experimentation units in lab-on-a-chip devices
Trends in Biotechnology, 2010'Lab-on-a-chip' technology (LOC) has now reached a mature state and is employed commonly in research in the life sciences. LOC devices make novel experimentation possible while providing a sophisticated environment for cellular investigation. As a next step, we introduce here the concept of a 'lab-in-a-cell': the use of a single cell as a minimal and ...
le Gac, Severine, van den Berg, Albert
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High-pressure liquid chromatography in lab-on-a-chip devices
Analytical and Bioanalytical Chemistry, 2007The miniaturization of high-pressure (or high-performance) liquid chromatography (LC) concerning the column inner diameter (i.d.) and volumetric flow rates is an ongoing trend that is mainly driven by the need to handle small volumes of complex sample, e.g., for the elucidation of physiological processes and identification of successful drug candidates,
Steffen, Ehlert, Ulrich, Tallarek
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Microfluidic Devices and Their Applications to Lab-on-a-Chip
2010Various microfluidic components and their characteristics, along with the demonstration of two recent achievements of lab-on-chip systems are reviewed and discussed. Many microfluidic devices and components have been developed during the past few decades, as introduced earlier for various applications. The design and development of microfluidic devices
Chong H. Ahn, Jin-Woo Choi
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Microsystem Engineering of Lab‐on‐a‐Chip Devices
2003Introduction Clean rooms Microfluidics - theoretical aspects Microfluidics - components Simulations in microfluidics Silicon and cleanroom processing Glass micromachining Polymer micromachining Packaging of microsystems Analytical chemistry on microsystems ...
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Lab-on-a-chip Devices for Advanced Biomedicines
The global miniature devices market is poised to surpass a valuation of $12–$15 billion USD by the year 2030. Lab-on-a-chip (LOC) devices are a vital component of this market. Comprising a network of microchannels, electrical circuits, sensors, and electrodes, LOC is a miniaturized integrated device platform used to streamline day-to-dayopenaire +1 more source