Results 1 to 10 of about 264,823 (308)

Microfluidics : the fur-free way towards personalised medicine in cancer therapy [PDF]

open access: yes, 2016
Microfluidic technology has great potential for complementing and, in some instances, replacing the use of animal models in the testing of medicines and in developing personalised treatments for cancer patients.
Bower, Ruth   +3 more
core  

Integrating GEO Database, Mendelian Randomization, and Molecular Docking to Identify HLA-C as a Potential Therapeutic Target for Periodontitis

open access: yesMediators of Inflammation
Conclusion: This study identifies HLA-C as a potential therapeutic target for periodontitis, with MD studies and molecular dynamic simulations highlighting metronidazole as a potential treatment.
ChengJi Shi   +7 more
doaj   +1 more source

Quasi-Optical Terahertz Microfluidic Devices for Chemical Sensing and Imaging

open access: yesMicromachines, 2016
We first review the development of a frequency domain quasi-optical terahertz (THz) chemical sensing and imaging platform consisting of a quartz-based microfluidic subsystem in our previous work. We then report the application of this platform to sensing
Lei Liu   +6 more
doaj   +1 more source

Synthesis of Polymer-Lipid Nanoparticles by Microfluidic Focusing for siRNA Delivery

open access: yesMolecules, 2016
Polyethylenimine (PEI) as a cationic polymer is commonly used as a carrier for gene delivery. PEI-800 is less toxic than PEI-25K but it is also less efficient.
Yujing Li   +11 more
doaj   +1 more source

Directed Placement for mVLSI Devices [PDF]

open access: yes, 2019
Continuous-flow microfluidic devices based on integrated channel networks are becoming increasingly prevalent in research in the biological sciences.
Brisk, P, Crites, B, Kong, K
core  

Continuous-Flow Ammoxidation of 2‑Methylpyrazine to 2‑Cyanopyrazine with High Space-Time Yield in a Microreactor

open access: yesACS Omega, 2022
Meixiu Wei   +5 more
doaj   +1 more source

Replicating Dynamic Immune Responses at Single‐Cell Resolution within a Microfluidic Human Skin Equivalent

open access: yesAdvanced Science
To enable in vitro investigation of human skin immunology, this study develops a microfluidic human skin equivalent (HSE) that supports the delivery of circulating immune cells via a vascular microchannel embedded within the dermis of a full‐thickness ...
Sarah A. Hindle   +5 more
doaj   +1 more source

High-Throughput Microfluidic Electroporation (HTME): A Scalable, 384-Well Platform for Multiplexed Cell Engineering

open access: yesBioengineering
Electroporation-mediated gene delivery is a cornerstone of synthetic biology, offering several advantages over other methods: higher efficiencies, broader applicability, and simpler sample preparation. Yet, electroporation protocols are often challenging
William R. Gaillard   +12 more
doaj   +1 more source

Microfluidic method for rapid turbidimetric detection of the DNA of Mycobacterium tuberculosis using loop-mediated isothermal amplification in capillary tubes [PDF]

open access: yes, 2015
We describe a microfluidic method for rapid isothermal turbidimetric detection of the DNA of Mycobacterium tuberculosis. Loop-mediated isothermal amplification is accomplished in capillary tubes for amplifying DNA in less than 15 min, and sensitivity and
Gill, P., Rafati, A.
core  

Capillary electrophoresis characterisation of a rapid prototyped PMMA chip for particle analysis [PDF]

open access: yes, 2010
Màster en Nanociència i NanotecnologiaA rapid and cheap method has been developed for the fabrication of a capillary electrophoresis chip for the preliminary characterization of particles.
Colom, Adai
core   +1 more source

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