Results 21 to 30 of about 102,565 (266)

Triple-channel microreactor for biphasic gas–liquid reactions: Photosensitized oxygenations

Beilstein Journal of Organic Chemistry, 2011
A triple-channel microreactor fabricated by means of a soft-lithography technique was devised for efficient biphasic gas–liquid reactions. The excellent performance of the microreactor was demonstrated by carrying out photosensitized oxygenations of α ...
Ram Awatar Maurya, Chan Pil Park, Dong-Pyo Kim   +2 more
doaj   +1 more source

CoVSense: Ultrasensitive Nucleocapsid Antigen Immunosensor for Rapid Clinical Detection of Wildtype and Variant SARS‐CoV‐2

Advanced Science, 2023
The widespread accessibility of commercial/clinically‐viable electrochemical diagnostic systems for rapid quantification of viral proteins demands translational/preclinical investigations.
Razieh Salahandish, Jae Eun Hyun, Fatemeh Haghayegh, Hamed Osouli Tabrizi, Shirin Moossavi, Sultan Khetani, Giancarlo Ayala‐Charca, Byron M. Berenger, Yan Dong Niu, Ebrahim Ghafar‐Zadeh, Amir Sanati Nezhad   +10 more
doaj   +1 more source

In Vitro 3D Modeling of Neurodegenerative Diseases

Bioengineering, 2023
The study of neurodegenerative diseases (such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, or amyotrophic lateral sclerosis) is very complex due to the difficulty in investigating the cellular dynamics within nervous tissue. Despite
Aurélie Louit, Todd Galbraith, François Berthod   +2 more
doaj   +1 more source

Evaluation of a microfluidic-based point-of-care prototype with customized chip for detection of bacterial clusters

Microbiology Spectrum
Bacterial infection clusters cause high mortality rates and healthcare costs due to excessive therapy and hygiene measures. The aim of this study was to develop an automated real-time PCR-based point-of-care (POC) system with a customized microfluidic ...
Janina Treffon, Nicole Isserstedt-John, Richard Klemm, Claudia Gärtner, Alexander Mellmann   +4 more
doaj   +1 more source

Study on the Motion Characteristics of Solid Particles in Fine Flow Channels by Ultrasonic Cavitation

Micromachines, 2022
Microjets caused by the cavitation effect in microchannels can affect the motion trajectory of solid particles in microchannels under ultrasonic conditions.
Mu Yuan, Chen Li, Jiangqin Ge, Qingduo Xu, Zhian Li   +4 more
doaj   +1 more source

Microfluidic Paper-Based Sample Concentration Using Ion Concentration Polarization with Smartphone Detection

Micromachines, 2016
A simple method for microfluidic paper-based sample concentration using ion concentration polarization (ICP) with smartphone detection is developed.
Xue Li, Yanan Niu, Yunyi Chen, Di Wu, Long Yi, Xianbo Qiu   +5 more
doaj   +1 more source

Deployable Lab-on-a-Chip Sensor for Colorimetric Measurements

Micromachines, 2023
The infield measurement of nutrients, heavy metals, and other contaminants in water is still a needed tool in environmental sciences. The Lab-on-a-chip approach can develop deployable instruments that use the standardized analytical assay in a ...
Stefan Gassmann, Till Schleifer, Helmut Schuette   +2 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source