Results 81 to 90 of about 87,269 (310)
Ruthenium Oxide pH Sensing for Organs-On-Chip Studies
Proceedings, 2018 A ruthenium oxide (RuOx) electrode is being developed as potentiometric pH sensor for organs-on-chip applications. Open-circuit potential (OCP) of the RuOx electrode showed a response of −58.05 mV/pH, with no cross-sensitivity to potentially ...
Esther Tanumihardja +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Characterization of femtosecond laser written waveguides for integrated biochemical sensing [PDF]
, 2007 Fluorescence detection is known to be one of the most sensitive among the different optical sensing techniques. This work focuses on excitation and detection of fluorescence emitted by DNA strands labeled with fluorescent dye molecules that can be ...
Cerullo, G. +8 more
core +1 more source
On-chip measurement of the Brownian relaxation frequency of magnetic beads using magnetic tunneling junctions [PDF]
, 2011 We demonstrate the detection of the Brownian relaxation frequency of 250 nm diameter magnetic beads using a lab-on-chip platform based on current lines for exciting the beads with alternating magnetic fields and highly sensitive magnetic tunnel junction ...
B. T. Dalslet +11 more
core +1 more source
Reference-Electrode Free pH Sensing Using Impedance Spectroscopy
Proceedings, 2018 We present a reference-electrode free sensor able to measure both pH and conductivitybased on impedance spectroscopy. The electrode is made of a layer of indium-tin-oxide (ITO).
Laura Folkertsma +4 more
doaj +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Vibrating nanoneedle and lab-on-chip microfluidics system for single cell mechanics [PDF]
, 2015 Single cell mechanics is a vital part of single cell analysis. It has attracted great interest among scientists as cell mechanics can be linked to early diagnosis of diseases. To date, several great findings have been achieved in the study of single cell
Rahman, Md. Habibur
core
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source
Self-organizing magnetic beads for biomedical applications
, 2011 In the field of biomedicine magnetic beads are used for drug delivery and to treat hyperthermia. Here we propose to use self-organized bead structures to isolate circulating tumor cells using lab-on-chip technologies.
Akoun +15 more
core +1 more source