Results 51 to 60 of about 126,902,087 (249)

Comparison of Illumination Methods for Flow-Through Optofluidic Biosensors

open access: yesMicromachines, 2023
Optofluidic biosensors have become an important medical diagnostic tool because they allow for rapid, high-sensitivity testing of small samples compared to standard lab testing.
Matthew Hamblin   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Correction: 3D printed nervous system on a chip

open access: yes, 2016
Correction for ‘3D printed nervous system on a chip’ by Blake N.
Meng, Fanben   +6 more
core   +1 more source

Fast electrically assisted regeneration of on-chip SERS substrates

open access: yes, 2022
S.2923-2927A microfluidic chip approach utilising integrated electrically connected stationary SERS targets based on inkjet-printed silver nanoparticles is presented.
Belder, Detlev   +7 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Systematic Review: Microfluidics and Plasmodium

open access: yesMicromachines, 2021
Malaria affects 228 million people worldwide each year, causing severe disease and worsening the conditions of already vulnerable populations. In this review, we explore how malaria has been detected in the past and how it can be detected in the future ...
Nicolas Thorne   +6 more
doaj   +1 more source

PDMS lab-on-a-chip fabrication using 3D printed templates

open access: yes, 2014
G. Comina's research stay at Linkoping University has been financed by the Peruvian National Council for Science and Technology (CONCYTEC). This research has been supported by grants from Linkoping Centre for Life Science Technologies (LIST), Sweden, and
Comina, G   +5 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Wearable Skin Sensors and Their Challenges: A Review of Transdermal, Optical, and Mechanical Sensors

open access: yesBiosensors, 2020
Wearable technology and mobile healthcare systems are both increasingly popular solutions to traditional healthcare due to their ease of implementation and cost-effectiveness for remote health monitoring.
Ammar Ahmad Tarar   +2 more
doaj   +1 more source

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