Results 61 to 70 of about 4,202,030 (239)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Label-Free Bioaerosol Sensing Using Mobile Microscopy and Deep Learning

, 2018
Conventional bioaerosol sensing requires the sampled aerosols in the field to be transferred to a laboratory for manual inspection, which can be rather costly and slow, also requiring a professional for labeling and microscopic examination of the samples.
Yibo Zhang (288948), Yi Luo, Aydogan Ozcan (138135), Cheng Chen (136164), Yair Rivenson, Maxwell Lutton (5861048), Yair Rivenson (3123522), Yi Luo (143206), Yichen Wu, Yibo Zhang, Aydogan Ozcan, Hongda Wang (33141), Hongda Wang, Zoltán Göröcs, Maxwell Lutton, Ayfer Calis, Yichen Wu (687233), Hatice Ceylan Koydemir, Xing Lin (534240), Ayfer Calis (5861045), Hatice Ceylan Koydemir (3123525), Cheng Chen, Xing Lin, Zoltán Göröcs (1895884)   +23 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Information‐Distilled Generative Label‐Free Morphological Profiling Encodes Cellular Heterogeneity

Advanced Science
Image‐based cytometry faces challenges due to technical variations arising from different experimental batches and conditions, such as differences in instrument configurations or image acquisition protocols, impeding genuine biological interpretation of ...
Michelle C. K. Lo, Dickson M. D. Siu, Kelvin C. M. Lee, Justin S. J. Wong, Maximus C. F. Yeung, Michael K. Y. Hsin, James C. M. Ho, Kevin K. Tsia   +7 more
doaj   +1 more source

Label-Free and Immobilization-Free Electrochemical Magnetobiosensor for Sensitive Detection of 5‑Hydroxymethylcytosine in Genomic DNA

, 2018
DNA 5-hydroxymethylcytosine (5-hmC) is an important epigenetic biomarker for tumorigenesis, and the loss of 5-hmC levels is associated with leukemia and melanoma cancers. However, it is a great challenge to discriminate 5-hmC from 5-methylcytosine (5-mC)
Juan Hu (676613), Meng Wang (124646), Chen-chen Li (4216513), Lin Cui (163750), Chun-yang Zhang (1405213)   +4 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Advancing Breath‐Based Diagnostics: 3D Mesh SERS Sensor Via Dielectrophoretic Alignment of Solution‐Processed Au Nanoparticle‐Decorated TiO2 Nanowires

Advanced Sensor Research
Surface enhanced Raman spectroscopy (SERS) is becoming an attractive analytical technique for the next generation of breath diagnostics. However, current SERS substrates present challenges related to fabrication cost, complexity, signal uniformity, and ...
Marios Constantinou, Christoforos Panteli, Louiza Potamiti, Mihalis I. Panayiotidis, Agapios Agapiou, Sotirios Christodoulou, Chrysafis Andreou   +6 more
doaj   +1 more source

Beyond fluorescence: A critical look at AI-powered brightfield analysis for T-cell killing assays

SLAS Discovery
This comment evaluates dela Cruz-Chuh et al.’s AI-based label-free workflow for analyzing T-cell mediated tumor killing via brightfield imaging.
Xiaoman Liu, Zihan Gao, Jiachun Xu
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

6. Label-free selective plane illumination microscopy of tissue samples

Journal of the Saudi Heart Association, 2017
Basic Science Research. Presentation type: Poster Presentation. Introduction: There is an increasing demand for non-invasive, label-free, three-dimensional imaging techniques for characterisation of optically turbid samples such as tissue engineered ...
Muteb Alharbi, Saleh Khonezan, Melissa Mather, Abdulrahman Almaymn   +3 more
doaj   +1 more source