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The Label-Free Fluorescence Detection of Inorganic and Organic Mercury Based on DNA-Templated Gold Nanoclusters. [PDF]
Biosensors (Basel)Chen Z, Zhang K.
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Analytical Biochemistry, 2013
A surface plasmon resonance (SPR) array imaging method is outlined for label-free cell profiling. Red blood cells (RBCs) were injected into a flow chamber on top of a spotted sensor surface. Spots contained antibodies to various RBC membrane antigens. A typical sensorgram showed an initial response corresponding to cell sedimentation (S) followed by a ...
Schasfoort, Richard B. M. +6 more
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A surface plasmon resonance (SPR) array imaging method is outlined for label-free cell profiling. Red blood cells (RBCs) were injected into a flow chamber on top of a spotted sensor surface. Spots contained antibodies to various RBC membrane antigens. A typical sensorgram showed an initial response corresponding to cell sedimentation (S) followed by a ...
Schasfoort, Richard B. M. +6 more
openaire +3 more sources
Recent advances in label-free detection in vitro and label-free imaging in vivo
Coordination Chemistry ReviewsChun-Yang Zhang
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Label-Free Proteomics of Serum
2008In this chapter we describe a method to analyze human serum with the goal of discovering disease-related changes in the serum proteome. The methodology is based on the removal of the six most abundant serum proteins by immunoaffinity chromatography. This step is followed by trypsin digestion and reversed-phase high-performance liquid chromatography ...
Govorukhina, N.I +2 more
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2009
Label-free biosensors are devices that use biological or chemical receptors to detect analytes (molecules) in a sample. They give detailed information on the selectivity, affinity, and, in many cases, also the binding kinetics and thermodynamics of an interaction. Although they can be powerful tools in the hands of a skilled user, there is often a lack
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Label-free biosensors are devices that use biological or chemical receptors to detect analytes (molecules) in a sample. They give detailed information on the selectivity, affinity, and, in many cases, also the binding kinetics and thermodynamics of an interaction. Although they can be powerful tools in the hands of a skilled user, there is often a lack
openaire +5 more sources
Label‐Free Optical Single‐Molecule Micro‐ and Nanosensors
Advanced Materials, 2018 Label-free optical sensor systems have emerged that exhibit extraordinary sensitivity for detecting physical, chemical, and biological entities at the micro/nanoscale. Particularly exciting is the detection and analysis of molecules, on miniature optical
Sivaraman Subramanian +2 more
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Label-Free Sensing on Microarrays
2016Microarrays of biological molecules such as DNAs, proteins, carbohydrates, and small molecules provide a high-throughput platform for screening tens of thousands of biomolecular interactions simultaneously, facilitating the functional characterization of these biomolecules in areas of genomics, proteomics, glycomics, and cytomics.
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2021
In this chapter, we focus on label-free biosensors. First, we look at sensors with optical detection. In this context, the Mach–Zehnder interferometer and the surface plasmon resonance offer the possibility to limit the optical examination to shallow surface layers. The second group are the gravimetric biosensors.
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In this chapter, we focus on label-free biosensors. First, we look at sensors with optical detection. In this context, the Mach–Zehnder interferometer and the surface plasmon resonance offer the possibility to limit the optical examination to shallow surface layers. The second group are the gravimetric biosensors.
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Label-Free Microelectronic PCR Quantification
Analytical Chemistry, 2006We present a robust and simple method for direct, label-free PCR product quantification using an integrated microelectronic sensor. The field-effect sensor can sequentially detect the intrinsic charge of multiple unprocessed PCR products and does not require sample processing or additional reagents in the PCR mixture.
Chih-Sheng Johnson, Hou +5 more
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