Results 71 to 80 of about 4,376,632 (304)
Label-Free Optical Single-Molecule Micro- and Nanosensors
, 2018 Label-free optical sensor systems have emerged that exhibit extraordinary sensitivity for detecting physical, chemical, and biological entities at the micro/nanoscale. Particularly exciting is the detection and analysis of molecules, on miniature optical
J Xavier (12827146) +4 more
core +3 more sources
Label-Free Biosensors for Cell Biology
International Journal of Electrochemistry, 2011 Label-free biosensors for studying cell biology have finally come of age. Recent developments have advanced the biosensors from low throughput and high maintenance research tools to high throughput and low maintenance screening platforms.
Ye Fang
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Label-Free Assays on the BIND System [PDF]
SLAS Discovery, 2004 Screening of biochemical interactions becomes simpler, less expensive, and more accurate when labels, such as fluorescent dyes, radioactive markers, and colorimetric reactions, are not required to quantify detected material. SRU Biosystems has developed a biosensor technology that is manufactured on continuous sheets of plastic film and incorporated ...
Brian T, Cunningham +9 more
openaire +2 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Label‐Free Photonic Biosensors: Key Technologies for Precision Diagnostics
ChemistryEuropeWith the rise of multidrug‐resistant pathogens, emerging zoonotic viruses, and the increasing prevalence of cancer, the modernization of clinical diagnostics has become a critical priority.
Maria Soler, Laura M. Lechuga
doaj +1 more source
Label-Free Chemiresistive Immunosensors for Viruses [PDF]
Environmental Science & Technology, 2010 We report development, characterization, and testing of chemiresistive immunosensors based on single polypyrrole (Ppy) nanowire for highly sensitive, specific, label free, and direct detection of viruses. Bacteriophages T7 and MS2 were used as safe models for viruses for demonstration.
Dhammanand J, Shirale +6 more
openaire +2 more sources
, 2023 Epigenetic dysregulation including DNA methylation and histone modifications is being increasingly recognized as a promising biomarker for the diagnosis and prognosis of cancer. Herein, we devised a label-free analytical toolbox comprising IR, UV–vis, CD
Suchetan Pal (1628932) +7 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Sensing and Bio-Sensing Research, 2020 Nanomaterials use in traditional spectroscopic assays has enabled the development of more sensitive and accessible methods with wider-range of applications.
Yulán Hernández +2 more
doaj +1 more source