Results 201 to 210 of about 518,105 (292)

Enhanced sensitivity in label-free live-cell imaging using multi-pass stimulated Raman scattering microscopy [PDF]

BIO Web of Conferences
Reynolds Joshua, Burd Shaun, Yen Tzu-Chieh (Jerry), Mondal Samsuzzoha, Wakatsuki Soichi, Kasevich Mark   +5 more
doaj   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Accelerated discovery of cell migration regulators using label-free deep learning-based automated tracking. [PDF]

Sci Adv
Chu T, Lim Y, Sun Y, Wu F, Castillo C, Hanna E, Wirtz D, Wu PH.   +7 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Label-Free Measurement of Ligand Interactions Using SABRE Hyperpolarization at Low Magnetic Fields. [PDF]

Anal Chem
Roy A, Hilty C.
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Label-Free Electrochemical Biosensors: An Updated Perspective Focused on Genosensing, Multiplexing, and Commercial Potential. [PDF]

Biosensors (Basel)
Carvalho JHS, Catai MAS, Bertolim LV, Freitas RC, Camargo JR, Brazaca LC, Janegitz BC.   +6 more
europepmc   +1 more source

Label-free technologies and pharmacology

Pharmacological Research, 2016
openaire   +2 more sources