Results 1 to 10 of about 403,277 (275)
Super-resolution label-free volumetric vibrational imaging [PDF]
Nature Communications, 2021 Super-resolution microscopy is often limited by photobleaching or uneven distribution of fluorophores. The authors present a label-free superresolution method termed VISTA, combining sample-expansion and vibrational imaging, with resolution down to 78 nm
Chenxi Qian +5 more
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Plasmonic nano-aperture label-free imaging (PANORAMA) [PDF]
Nature Communications, 2020 Here, the authors report on an imaging method based on localized surface plasmon resonance excitation, employing gold nanodisk arrays as substrates that enable imaging of transparent dielectric particles of several sizes.
Nareg Ohannesian +3 more
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Label-Free Imaging of DNA Interactions with 2D Materials. [PDF]
ACS Photonics, 2023 AbstractTwo-dimensional (2D) materials offer potential as substrates for biosensing devices, as their properties can be engineered to tune interactions between the surface and biomolecules. Yet, not many methods can measure these interactions in a liquid environment without introducing labeling agents such as fluorophores.
Sülzle J +6 more
europepmc +3 more sources
Label-Free Biosensor Imaging on Photonic Crystal Surfaces [PDF]
Sensors, 2015 We review the development and application of nanostructured photonic crystal surfaces and a hyperspectral reflectance imaging detection instrument which, when used together, represent a new form of optical microscopy that enables label-free, quantitative,
Yue Zhuo, Brian T. Cunningham
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Artificial confocal microscopy for deep label-free imaging. [PDF]
Nat Photonics, 2023 Widefield microscopy methods applied to optically thick specimens are faced with reduced contrast due to spatial crosstalk, in which the signal at each point is the result of a superposition from neighboring points that are simultaneously illuminated. In 1955, Marvin Minsky proposed confocal microscopy as a solution to this problem.
Chen X +10 more
europepmc +4 more sources
Nanophotonic sensing and label-free imaging of extracellular vesicles [PDF]
Light: Science & ApplicationsThis review examines imaging-based nanophotonic biosensing and interferometric label-free imaging, with a particular focus on vesicle detection. It specifically compares dielectric and plasmonic metasurfaces for label-free protein and extracellular ...
Isabel Barth, Hakho Lee
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Single‐Exosome Counting and 3D, Subdiffraction Limit Localization Using Dynamic Plasmonic Nanoaperture Label‐Free Imaging [PDF]
Advanced NanoBiomed Research, 2023 Blood‐circulating exosomes as a disease biomarker have great potential in clinical applications as they contain molecular information about their parental cells.
Mohammad Sadman Mallick +3 more
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Label-free imaging for quality control of cardiomyocyte differentiation [PDF]
Nature Communications, 2021 Differentiation of hPSCs to cardiomyocytes suffers from high variability. Here the authors report a label-free live cell imaging platform based on autofluorescence imaging to enable the prediction of cardiomyocyte differentiation efficiency from hPSCs.
Tongcheng Qian +5 more
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Non-optical, label-free electrical capacitance imaging of microorganisms
mBioMany fundamental insights into microbiology have come from imaging, which is typically synonymous with optical techniques. However, the sample preparation needed for many optical microscopy methods, such as labeling, fixing, or genetic modification ...
Joseph T. Incandela +4 more
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Physiological Reports, 2022 Label‐free fluorescence imaging of kidney sections can provide important morphological information, but its utility has not been tested in a histology processing workflow.
Angela R. Sabo +7 more
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