Results 171 to 180 of about 403,277 (275)

Label-free droplet image analysis with Cellprofiler

AbstractDroplet microfluidic methods used for microbiological experiments are fast, cost-effective, and provide high-throughput data. However, analysis of such image data can be difficult, and detection of molecular labels is limited by microscope parameters.Currently, there is lack of user-friendly methods to analyse a large volume of label-free ...
Dániel Kácsor, Merili Saar-Abroi, Triini Olman, Simona Bartkova, Ott Scheler   +4 more
openaire   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Quantitative Phase Macroscopic System for Label-Free Imaging of Tissue Sections

Electrica, 2021
Muhammed Fatih Toy
doaj   +1 more source

Quadrant darkfield for label-free imaging of intracellular puncta. [PDF]

J Biomed Opt
Moustafa TE, Belote RL, Polanco ER, Judson-Torres RL, Zangle TA.   +4 more
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Real-time label-free imaging of living crystallization-driven self-assembly. [PDF]

Nat Commun
Guo Y, Xia T, Walter V, Xie Y, Rho JY, Xiao L, O'Reilly RK, Wallace MI.   +7 more
europepmc   +1 more source

Label-Free Imaging Techniques to Evaluate Metabolic Changes Caused by Toxic Liver Injury in PCLS. [PDF]

Int J Mol Sci, 2023
Rodimova S, Mozherov A, Elagin V, Karabut M, Shchechkin I, Kozlov D, Krylov D, Gavrina A, Bobrov N, Zagainov V, Zagaynova E, Kuznetsova D.   +11 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Planar device-enabled speckle illumination for dark-field label-free imaging beyond the diffraction limit. [PDF]

Proc Natl Acad Sci U S A
Fan Z, You X, Zhang D.
europepmc   +1 more source

Label-Free Imaging of Catalytic H₂O₂ Decomposition on Single Colloidal Pt Nanoparticles Using Nanofluidic Scattering Microscopy. [PDF]

ACS Nano, 2023
Altenburger B, Andersson C, Levin S, Westerlund F, Fritzsche J, Langhammer C.   +5 more
europepmc   +1 more source