Results 211 to 220 of about 403,277 (275)

Recent advances in label-free imaging techniques based on nonlinear optical microscopy to reveal the heterogeneity of the tumor microenvironment. [PDF]

Biophys Rev
Chakraborty I, Mazumder N, Gogoi A, Chen MC, Zhuo GY.   +4 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Development of a noninvasive and label-free imaging system for human interfollicular epidermal stem cells based on cell morphology. [PDF]

Skin Res Technol
Miyachi K, Shiraishi T, Sanada A, Ishii Y, Hirose O, Yamada T, Igarashi T, Hasegawa S, Arima M, Iwata Y, Sugiura K, Akamatsu H.   +11 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

A high-resolution phase-contrast microscopy system for label-free imaging in living cells. [PDF]

Cell Struct Funct
Shimasaki K, Okemoto-Nakamura Y, Saito K, Fukasawa M, Katoh K, Hanada K.   +5 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Plasmonic nano-aperture label-free imaging of single small extracellular vesicles for cancer detection. [PDF]

Commun Med (Lond)
Ohannesian N, Mallick MS, He J, Qiao Y, Li N, Shaitelman SF, Tang C, Shinn EH, Hofstetter WL, Goltsov A, Hassan MM, Hunt KK, Lin SH, Shih WC.   +13 more
europepmc   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

A biosensor-integrated filtration device for nanoparticle isolation and label-free imaging.

Lab Chip
Liu L, Ayupova T, Umrao S, Akin LD, Lee HK, Tibbs J, Wang X, Demirci U, Cunningham BT.   +8 more
europepmc   +1 more source

Permittivity tensor imaging: modular label-free imaging of 3D dry mass and 3D orientation at high resolution. [PDF]

Nat Methods
Yeh LH, Ivanov IE, Chandler T, Byrum JR, Chhun BB, Guo SM, Foltz C, Hashemi E, Perez-Bermejo JA, Wang H, Yu Y, Kazansky PG, Conklin BR, Han MH, Mehta SB.   +14 more
europepmc   +1 more source