Results 231 to 240 of about 403,277 (275)

Full-field optical coherence microscopy enables high-resolution label-free imaging of the dynamics of live mouse oocytes and early embryos. [PDF]

Commun Biol
Morawiec S, Ajduk A, Stremplewski P, Kennedy BF, Szkulmowski M.   +4 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Label-free imaging of 3D pluripotent stem cell differentiation dynamics on chip

, 2022
Atwell S, Waibel DJE, Boushehri SS, Marr C, Meier M.   +4 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Roadmap on label-free super-resolution imaging

Label-free super-resolution (LFSR) imaging relies on light-scattering processes in nanoscale objects without a need for fluorescent (FL) staining required in super-resolved FL microscopy. The objectives of this Roadmap are to present a comprehensive vision of the developments, the state-of-the-art in this field, and to discuss the resolution boundaries
Astratov, VN, Ben Sahel, Y, Eldar, YC, Huang, L, Ozcan, A, Zheludev, N, Zhao, J, Burns, Z, Liu, Z, Narimanov, E, Goswami, N, Popescu, G, Pfitzner, E, Kukura, P, Hsiao, Y-T, Hsieh, C-L, Abbey, B, Diaspro, A, LeGratiet, A, Bianchini, P, Shaked, NT, Simon, B, Verrier, N, Debailleul, M, Haeberle, O, Wang, S, Liu, M, Bai, Y, Cheng, J-X, Kariman, BS, Fujita, K, Sinvani, M, Zalevsky, Z, Li, X, Huang, G-J, Chu, S-W, Tzang, O, Hershkovitz, D, Cheshnovsky, O, Huttunen, MJ, Stanciu, SG, Smolyaninova, VN, Smolyaninov, II, Leonhardt, U, Sahebdivan, S, Wang, Z, Luk'yanchuk, B, Wu, L, Maslov, AV, Jin, B   +49 more
openaire   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

High-resolution, large field-of-view label-free imaging via aberration-corrected, closed-form complex field reconstruction. [PDF]

Nat Commun
Cao R, Shen C, Yang C.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

High-volume, label-free imaging for quantifying single-cell dynamics in induced pluripotent stem cell colonies. [PDF]

PLoS One
Asmar AJ, Benson ZA, Peskin AP, Chalfoun J, Simon M, Halter M, Plant AL.   +6 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source