Label-free imaging of thick tissue at 1550nm using a femtosecond optical parametric generator [PDF]
We have developed a simple wavelength tunable optical parametric generator (OPG), emitting broad band ultrashort pulses with peak wavelengths at 1530-1790 nm, for nonlinear label-free microscopy.
Cobb, Stuart +6 more
core +1 more source
Highly Sensitive Intravascular Photoacoustic Imaging with a Collinear Catheter Probe [PDF]
A collinear catheter for label-free intravascular photoacoustic imaging was developed with a diameter of 1.6 mm. The collinear overlap between optical and acoustic waves enabled photoacoustic imaging of a human coronary artery from lumen to perivascular ...
Cao, Yingchun +6 more
core +1 more source
Inverse scattering for reflection intensity phase microscopy [PDF]
Reflection phase imaging provides label-free, high-resolution characterization of biological samples, typically using interferometric-based techniques.
Chaumet, Patrick C. +4 more
core +3 more sources
Label-free optical imaging of membrane potential
Offering high temporal resolution, voltage imaging is an important and essential technique in neuroscience. Among different optical imaging approaches, the label-free approach remains attractive due to its unique value coming from free of exogenous chromophores.
Hyeon Jeong Lee +2 more
openaire +3 more sources
Label-free imaging of gelatin-containing hydrogel scaffolds [PDF]
Composite hyaluronic acid (HA) hydrogels containing gelatin are used in regenerative medicine as tissue-mimicking scaffolds for improving stem cell survival. Once implanted, it is assumed that these biomaterials disintegrate over time, but at present there is no non-invasive imaging technique available with which such degradation can be directly ...
Yajie, Liang +5 more
openaire +2 more sources
Fast label-free multilayered histology-like imaging of human breast cancer by photoacoustic microscopy [PDF]
The goal of breast-conserving surgery is to completely remove all of the cancer. Currently, no intraoperative tools can microscopically analyze the entire lumpectomy specimen, which results in 20 to 60% of patients undergoing second surgeries to achieve ...
Aft, Rebecca L +7 more
core +3 more sources
Label-Free Molecular Imaging of Living Cells
Optical signals based on Raman scattering, coherent anti-Stokes Raman scattering (CARS), and harmonic generation can be used to image biological molecules in living cells without labeling. Both Raman scattering and CARS signals can be used to detect frequencies of molecular vibrations and to obtain the molecular distributions in samples.
Katsumasa, Fujita, Nicholas Isaac, Smith
openaire +2 more sources
Surface-enhanced Raman imaging of cell membrane by a highly homogeneous and isotropic silver nanostructure [PDF]
Label-free, surface-enhanced Raman spectroscopic imaging of the challenging red blood cell membrane is achieved by using a near-hyperuniform disordered plasmonic nanostructure of silver nanoparticles.
DOCHSHANOV, ALDEN +4 more
core +1 more source
Label-free molecular imaging of the kidney
In this review, we will highlight technologies that enable scientists to study the molecular characteristics of tissues and/or cells without the need for antibodies or other labeling techniques. Specifically, we will focus on matrix-assisted laser desorption/ionization imaging mass spectrometry, infrared spectroscopy, and Raman spectroscopy.
Boone M, Prentice +2 more
openaire +2 more sources
Label-free multimodal imaging of infected Galleria mellonella larvae
Non-linear imaging modalities have enabled us to obtain unique morpho-chemical insights into the tissue architecture of various biological model organisms in a label-free manner.
Elsie Quansah +10 more
doaj +1 more source

