Results 191 to 200 of about 666,217 (308)

Investigating the Conformational Diversity of the TMR-3 Aptamer. [PDF]

J Am Chem Soc
Gauger M, Duchardt-Ferner E, Halbritter AJ, Hetzke T, Sigurdsson ST, Wöhnert J, Prisner TF.   +6 more
europepmc   +1 more source

Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro, Manuela Dicarlo, Chiara Zecca, Daniele Urso, Maria Teresa Dell'Abate, Davide Vilella, Francesco Borlizzi, Roberta Zerlotin, Angela Oranger, Graziana Colaianni, Silvia Colucci, Maria Grano, Giancarlo Logroscino   +12 more
wiley   +1 more source

Protocol for the economic evaluation of individualised (early) patient-directed rehabilitation versus standard rehabilitation after surgical repair of the rotator cuff of the shoulder (RaCeR 2). [PDF]

BMJ Open
Manca A, Premji S, Gc VS, Chen T, Mazuquin B, Fakis A, Bateman M, Moffatt M, Littlewood C.   +8 more
europepmc   +1 more source

Analysis of the Longitudinal Behavior of Serum Levels of Soluble Flt1 and Placental Growth Factor in Pregnant Patients With Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective This study analyzed longitudinal trajectories of soluble Flt1 (sFlt1) levels, placenta growth factor (PlGF) levels, and sFlt1:PlGF ratios in a cohort of pregnant patients with systemic lupus erythematosus (SLE). Methods Blood samples were collected (14–18, 24–26, 30–32, 34–36, and 38–40 weeks), stored at −80°C, and evaluated for serum levels ...
Nilson R. de Jesús, Guilherme R. de Jesús, Marcela I. Lacerda, Flávia C. dos Santos, Jeane de S Nogueira, Luiz Cristóvão Porto, Evandro S. F. Coutinho, Evandro M. Klumb   +7 more
wiley   +1 more source

Add-on or switch to vibegron in patients with overactive bladder insufficiently responding to initial 4-week antimuscarinics: a randomised, parallel-group, multicentre trial (<b>ADVISR</b>) <b>protocol</b>. [PDF]

BMJ Open
Yamamoto T, Yoshida S, Maezawa Y, Tamiya T, Toide M, Fukushima H, Uehara S, Araki S, Ito M, Kobayashi S, Yoshinaga A, Kawamura N, Takazawa R, Sakai Y, Ootsuka Y, Tsukamoto T, Nagahama K, Tanaka H, Kitabayashi R, Hanazawa R, Ishiguro M, Sato H, Koike R, Fujii Y.   +23 more
europepmc   +1 more source

Association of Higher Levels of High‐Sensitivity C‐Reactive Protein With Future Development of Psoriatic Arthritis in Psoriasis: A Prospective Cohort Study

Arthritis Care &Research, EarlyView.
Objective We aimed to assess whether high‐sensitivity C‐reactive protein (hsCRP) levels could predict the development of psoriatic arthritis (PsA) in patients with psoriasis. Methods We analyzed data from a prospective cohort of patients with psoriasis without PsA at enrollment.
Lihi Eder, Xianwei Li, Vinod Chandran, Cheryl F. Rosen, Richard J. Cook, Dafna D. Gladman   +5 more
wiley   +1 more source

Protocol for spatial metabolomics and isotope tracing in the mouse brain. [PDF]

STAR Protoc
Sontising W, Yanchik-Slade F, Rodriguez-Navas C, Hossen MA, Gonzalez-Rodriguez M, Vaynshteyn J, Yamaguchi S, Boutaghou MN, Marin-Valencia I.   +8 more
europepmc   +1 more source

Screening for Social Determinants of Health in Patients with Systemic Lupus Erythematosus: A Point‐of‐Care Feasibility Study

Arthritis Care &Research, Accepted Article.
Objectives Social determinants of health (SDoH) can impact outcomes but are not routinely screened for in US outpatient rheumatology clinics. This study determined the feasibility of routine point‐of‐care SDoH screening among patients with systemic lupus erythematosus (SLE), and associated barriers and facilitators at the physician, care team, and ...
S. Sam Lim, Vijay R. Nadipelli, Michelle Bruno, Daphne Lew, Bernard Rubin, Charmayne M. Dunlop‐Thomas, Kelsey Hulcher, Kristi R. Mitchell, Lydia Demetriou, Jeff Berko, Jason Bao, Alfred H.J. Kim   +11 more
wiley   +1 more source

Evaluation of out-of-distribution detection methods for data shifts in single-cell transcriptomics. [PDF]

Brief Bioinform
Theunissen L, Mortier T, Saeys Y, Waegeman W.   +3 more
europepmc   +1 more source

Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib

ACR Open Rheumatology, EarlyView.
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi, Ennio Giulio Favalli, Gabriella Maioli, Elena Agape, Marzia Rossato, Matteo Paini, Adriana Severino, Barbara Vigone, Martina Biggioggero, Elena Trombetta, Roberto Caporali, Lorenzo Beretta   +11 more
wiley   +1 more source