Results 221 to 230 of about 551,720 (296)

Clinical Trial: Dose-Finding Study of Linaprazan Glurate, A Novel Potassium-Competitive Acid Blocker, Versus Lansoprazole for the Treatment of Erosive Oesophagitis. [PDF]

Aliment Pharmacol Ther
Sharma P, Vaezi M, Unge P, Andersson K, Larsson K, Popadiyn I, Rosenholm M, Rosztóczy A, Yektaei E, Armstrong D.   +9 more
europepmc   +1 more source

Sequence Analysis to Phenotype Health Care Patterns in Adults With Musculoskeletal Conditions Using Primary Care Electronic Health Records

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to apply sequence analysis (SA) to phenotype health care patterns of adult patients with musculoskeletal (MSK) conditions using primary care electronic health records and to investigate the association between these health care patterns and patients’ self‐reported outcomes after consultation.
Smitha Mathew, George Peat, Emma Parry, Ross Wilkie, Kelvin P. Jordan, Jonathan C. Hill, Dahai Yu   +6 more
wiley   +1 more source

Exploring the acceptability, appropriateness, feasibility and satisfaction of an implementation strategy for out-of-HOspital administration of the Long-Acting combination of cabotegravir and rilpivirine as an optional therapy for HIV in Spain (the HOLA study)-a hybrid implementation-effectiveness, phase IV, double-arm, open-label, multicentric study: study protocol. [PDF]

BMJ Open
Negredo E, Hernández-Sánchez D, Álvarez-López P, Falcó V, Rivero À, Jusmet J, Cuerda Palomo MÁ, Flores de la Cruz AB, Pavón JM, Llavero N, Campany D, Faus V, Broto-Cortés C, Bailón L, Aguilar D, Ruiz F, Miranda C, Puig J, Rovira D, Olalla J.   +19 more
europepmc   +1 more source

Analysis of the Longitudinal Behavior of Serum Levels of Soluble Flt1 and Placental Growth Factor in Pregnant Patients With Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective This study analyzed longitudinal trajectories of soluble Flt1 (sFlt1) levels, placenta growth factor (PlGF) levels, and sFlt1:PlGF ratios in a cohort of pregnant patients with systemic lupus erythematosus (SLE). Methods Blood samples were collected (14–18, 24–26, 30–32, 34–36, and 38–40 weeks), stored at −80°C, and evaluated for serum levels ...
Nilson R. de Jesús, Guilherme R. de Jesús, Marcela I. Lacerda, Flávia C. dos Santos, Jeane de S Nogueira, Luiz Cristóvão Porto, Evandro S. F. Coutinho, Evandro M. Klumb   +7 more
wiley   +1 more source

Real-life neovascular AMD treatment considering reimbursement in Turkiye: One-year comparison of switching to intravitreal ranibizumab or aflibercept after treatment failure with three loading intravitreal bevacizumab injections. [PDF]

North Clin Istanb
Sevik MO, Tiras NZ, Aykut A, Yigit DD, Sahin O.   +4 more
europepmc   +1 more source

Two‐Year Follow‐Up of a Multidisciplinary Lifestyle Intervention for Rheumatoid Arthritis and Osteoarthritis

Arthritis Care &Research, Accepted Article.
Objective The Plants for Joints intervention (PFJ), including a whole‐food plant‐based diet, exercise, and stress reduction, reduced signs and symptoms of rheumatoid arthritis (RA) or metabolic syndrome‐associated hip or knee osteoarthritis (MSOA) compared to usual care. This study examined outcomes two years later. Methods After two 16‐week randomized
Carlijn A. Wagenaar, Wendy Walrabenstein, Marike van der Leeden, Franktien Turkstra, Martijn Gerritsen, Jos W.R. Twisk, Maarten Boers, Martin van der Esch, Henriët van Middendorp, Peter J.M. Weijs, Dirkjan van Schaardenburg   +10 more
wiley   +1 more source

Reliability-enhanced data cleaning in biomedical machine learning using inductive conformal prediction. [PDF]

PLoS Comput Biol
Zhan X, Xu Q, Zheng Y, Lu G, Gevaert O.
europepmc   +1 more source

Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis

Advanced Biology, EarlyView.
Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard, Kaja Borup Løvschall, Mireia Casanovas Montasell, Clara Bakkegaard Cramer, Pere Monge Marcet, Andreas Bøtker Pedersen, Josefine Hammer Jakobsen, Alexander N. Zelikin   +7 more
wiley   +1 more source

A Strategy to Compare Single-Cell RNA Sequencing Data Sets Provides Phenotypic Insight into Cellular Heterogeneity Underlying Biological Similarities and Differences Between Samples. [PDF]

Bioinform Biol Insights
Wilkinson DC, Tallman E, Ashraf M, Romer TG, Lee J, Burnett B, Bushel PR.   +6 more
europepmc   +1 more source

Safety, tolerability, and immunogenicity of pentavalent meningococcal MenABCWY vaccine in healthy infants: A phase 2b randomized clinical trial. [PDF]

Hum Vaccin Immunother
Martinon-Torres F, Lamberth E, Natalini Martinez S, Salamanca de la Cueva I, Zolotas L, Oladipupo I, Maguire JD, Trammel J, O'Neill R, Liberator PA, Peyrani P, Jodar L, Gruber WC, Anderson AS, Beeslaar J.   +14 more
europepmc   +1 more source