Results 71 to 80 of about 695,542 (311)

Structured diabetes education program for improving self-care behavior in primary care settings of Puducherry: Evidence from a randomized controlled trial

Indian Journal of Community Medicine, 2019
Context: Diabetes self-management education plays a critical role in improving patients' clinical outcome and quality of life. Aims: This study aims to study the effectiveness of a structured diabetes educational program on improvement of self-care ...
Mamta Gehlawat, Subitha Lakshminarayanan, Sitanshu Sekhar Kar   +2 more
doaj   +1 more source

Poor Man's Content Centric Networking (with TCP) [PDF]

, 2011
A number of different architectures have been proposed in support of data-oriented or information-centric networking. Besides a similar visions, they share the need for designing a new networking architecture.
Budigere, K., Ott, J., Perkins, C.S., Sarolahti, P.   +3 more
core   +1 more source

RIBAR and xRIBAR: methods for reproducible relative MS/MS-based label-free protein quantification [PDF]

, 2011
Mass spectrometry-driven proteomics is increasingly relying on quantitative analyses for biological discoveries. As a result, different methods and algorithms have been developed to perform relative or absolute quantification based on mass spectrometry ...
Colaert, Niklaas, Gevaert, Kris, Martens, Lennart   +2 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

Paraffin embedding of the whole human cerebral hemisphere to assess arterial distribution territories

EXCLI Journal : Experimental and Clinical Sciences
Commonly used to decode the human brain's structural complexity, ex vivo dissection focuses on a given structure or region but cannot depict the whole brain organization (for example, its arterial distribution territories).
Mykyta Smirnov, Frédéric Andersson, Laurent Barantin, Igor Lima Maldonado, Christophe Destrieux   +4 more
doaj   +1 more source

Effect of a conventional energy-restricted modified diet with or without meal replacement on weight loss and cardiometabolic risk profile in overweight women

Nutrition & Metabolism, 2011
Background Abdominal obesity, atherogenic dyslipidemia and hypertension are essential risk factors for cardiovascular diseases. Several studies showed favorable effects of weight loss in overweight subjects on cardiometabolic risk profile.
Schäfer Sandy, Lemperle Martin, Bitterlich Norman, Folberth-Vögele Anke, Metzner Christine E, Alteheld Birgit, Stehle Peter, Siener Roswitha   +7 more
doaj   +1 more source

Efficacy and safety of nelfinavir in asymptomatic and mild COVID-19 patients: a structured summary of a study protocol for a multicenter, randomized controlled trial

Trials, 2021
Objectives The aim of this trial is to evaluate the antiviral efficacy, clinical efficacy, and safety of nelfinavir in patients with asymptomatic and mild COVID-19.
Naoki Hosogaya, Taiga Miyazaki, Yuri Fukushige, Sachiko Takemori, Shinpei Morimoto, Hiroshi Yamamoto, Makoto Hori, Tomoya Kurokawa, Yohei Kawasaki, Michiko Hanawa, Yasuhisa Fujii, Hideki Hanaoka, Shingo Iwami, Koichi Watashi, Satoshi Yamagoe, Yoshitsugu Miyazaki, Takaji Wakita, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae, Shigeru Kohno, Nelfinavir Study Group   +21 more
doaj   +1 more source

Simultaneous Deep Transfer Across Domains and Tasks

, 2015
Recent reports suggest that a generic supervised deep CNN model trained on a large-scale dataset reduces, but does not remove, dataset bias. Fine-tuning deep models in a new domain can require a significant amount of labeled data, which for many ...
Darrell, Trevor, Hoffman, Judy, Saenko, Kate, Tzeng, Eric   +3 more
core   +1 more source