Results 301 to 310 of about 2,887,200 (357)

Brodalumab for Moderate-to-Severe Psoriasis: A Comprehensive Review of Efficacy, Safety, and Clinical Positioning. [PDF]

Biologics
Babaei N, Gill M, Cervantes M, Kim D, Yang S, Wu JJ.   +5 more
europepmc   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Efficacy and Safety of Switching from Ranibizumab to Brolucizumab in Age-Related Macular Degeneration: Multicenter Real-World Outcomes. [PDF]

Clin Ophthalmol
Hejsek L, Hrevuš M, Burova M, Beran D, Cyžová Z, Penčák M, Pařilová T, Liláková D, Veith M.   +8 more
europepmc   +1 more source

The Off-Label Use of Selective Serotonin Reuptake Inhibitors for Sexual Behavior Management: Risks and Considerations. [PDF]

Healthcare (Basel)
Shaw J, Lai C, Bota P, Le A, Andricioaei A, Tran T, Allee T.   +6 more
europepmc   +1 more source

Five-Year Safety and Efficacy Outcomes with Ofatumumab in Patients with Relapsing Multiple Sclerosis. [PDF]

Neurol Ther
Hauser SL, Cohen JA, de Sèze J, Meuth SG, Giacomini PS, Nakahara J, Oreja-Guevara C, Robertson D, Wray S, Bhatt A, Hu X, Xi J, Piccolo R, Jehl V, Sullivan R, Boer I, Wiendl H, Kappos L.   +17 more
europepmc   +1 more source

ASReview LAB v.2: Open-source text screening with multiple agents and a crowd of experts. [PDF]

Patterns (N Y)
de Bruin J, Lombaers P, Kaandorp C, Teijema J, van der Kuil T, Yazan B, Dong A, van de Schoot R.   +7 more
europepmc   +1 more source

Low-dose oral minoxidil for the management of vismodegib-induced alopecia. [PDF]

JAAD Case Rep
Newcomer J, Aghazadeh N.
europepmc   +1 more source

Up-recycling of waste wood into value-added room temperature phosphorescent materials. [PDF]

Nat Commun
Yin WM, Dang B, Guo S, Sun M, Guo YR, Liu S, Li S, Li J, James TD, Chen Z.   +9 more
europepmc   +1 more source