Results 31 to 40 of about 278,707 (295)
Architecture, design, and modeling of the OPSnet asynchronous optical packet switching node [PDF]
An all-optical packet-switched network supporting multiple services represents a long-term goal for network operators and service providers alike.
Harle, D.A., Vanderbauwhede, W.A.
core +1 more source
CR-LDP as the signaling protocol at networking multiprotocol label switching
This paper reports raised events and results from the use of CR-LDP as a possible protocol of signal point MPLS, in order determine whether QoS warranties the desired quality for intensive bandwidth applications.
Danilo López +2 more
doaj +1 more source
Optimizing segment routing using evolutionary computation [PDF]
Segment Routing (SR) combines the simplicity of Link-State routing protocols with the flexibility of Multiprotocol Label Switching (MPLS). By decomposing forwarding paths into segments, identified by labels, SR improves Traffic Engineering (TE) and ...
McKeown +6 more
core +1 more source
Bayesian solutions to the label switching problem [PDF]
The label switching problem, the unidentifiability of the permutation of clusters or more generally latent variables, makes interpretation of results computed with MCMC sampling difficult. We introduce a fully Bayesian treatment of the permutations which
A. Jasra +11 more
core +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Switching to riociguat: a potential treatment strategy for the management of CTEPH and PAH
Currently, five classes of drug are approved for the treatment of pulmonary arterial hypertension (PAH): phosphodiesterase 5 inhibitors (PDE5i); endothelin receptor antagonists; prostacyclin analogs; the IP receptor agonist selexipag; and the soluble ...
Raymond L. Benza +6 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Tunable 4-channel ultra-dense WDM demultiplexer with III-V photodiodes integrated in silicon-on-insulator [PDF]
A tunable 4-channel ultra-dense WDM demultiplexer with 0.25nm channel spacing is demonstrated with III-V photodiodes integrated on Silicon-on-Insulator using rib waveguides.
De Heyn, Peter +4 more
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Kidney transplant recipients (KTRs) have a suboptimal immune response to COVID-19 vaccination due to the effects of immunosuppression, mostly mycophenolic acid (MPA).
Athiphat Banjongjit +12 more
doaj +1 more source

