Results 91 to 100 of about 25,867,085 (318)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Self-Supervised Learning for Vehicle Noise Prediction With Limited Labeled Data

open access: yesIEEE Access
With advancements in artificial intelligence, its application for developing quieter vehicles is increasingly researched in the automotive industry.
Sunhyeok Hwang, Seoung Bum Kim
doaj   +1 more source

Deep CNN Framework for Audio Event Recognition using Weakly Labeled Web Data

open access: yes, 2017
The development of audio event recognition models requires labeled training data, which are generally hard to obtain. One promising source of recordings of audio events is the large amount of multimedia data on the web.
Kumar, Anurag, Raj, Bhiksha
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Classification of Few Labeled Images Based on Integrated GMM Clustering

open access: yesXibei Gongye Daxue Xuebao, 2019
In order to improve the classifier classification accuracy of by using convolutional neural network training, a large amount of labeled data is often required, but sometimes labeled data is not easily obtained.This paper proposes a solution based on the ...

doaj   +1 more source

Eculizumab monotherapy for NMOSD: Data from PREVENT and its open-label extension [PDF]

open access: hybrid, 2021
Sean J. Pittock   +13 more
openalex   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Fine-grained fashion classification with limited labeled data via generative augmentation

open access: yesIntelligent and Converged Networks
Fine-grained classification of fashion items is essential for enhancing user experiences in online shopping, enabling more effective categorization and personalized recommendations. While recent advances in Artificial Intelligence (AI) have shown promise,
Hongbi Jeong   +4 more
doaj   +1 more source

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