Results 91 to 100 of about 2,965,444 (278)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Fine-grained fashion classification with limited labeled data via generative augmentation

open access: yesIntelligent and Converged Networks
Fine-grained classification of fashion items is essential for enhancing user experiences in online shopping, enabling more effective categorization and personalized recommendations. While recent advances in Artificial Intelligence (AI) have shown promise,
Hongbi Jeong   +4 more
doaj   +1 more source

Deep CNN Framework for Audio Event Recognition using Weakly Labeled Web Data

open access: yes, 2017
The development of audio event recognition models requires labeled training data, which are generally hard to obtain. One promising source of recordings of audio events is the large amount of multimedia data on the web.
Kumar, Anurag, Raj, Bhiksha
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Clustering and Labeling Auction Fraud Data

open access: yes, 2019
Although shill bidding is a common auction fraud, it is however very tough to detect. Due to the unavailability and lack of training data, in this study, we build a high-quality labeled shill bidding dataset based on recently collected auctions from eBay.
Alzahrani, Ahmad, Sadaoui, Samira
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Discriminatory Target Learning: Mining Significant Dependence Relationships from Labeled and Unlabeled Data

open access: yesEntropy, 2019
Machine learning techniques have shown superior predictive power, among which Bayesian network classifiers (BNCs) have remained of great interest due to its capacity to demonstrate complex dependence relationships.
Zhi-Yi Duan   +4 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Automatic Labeled LiDAR Data Generation and Distance-Based Ensemble Learning for Human Segmentation

open access: yesIEEE Access, 2019
Following the improvements in deep neural networks, state-of-the-art networks have been proposed for human segmentation using point clouds captured by light detection and ranging.
Wonjik Kim   +3 more
doaj   +1 more source

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