Results 111 to 120 of about 25,867,085 (318)

Galaxy Morphology Classification via Deep Semisupervised Learning with Limited Labeled Data

open access: yesThe Astrophysical Journal Supplement Series
Galaxy morphology classification plays a crucial role in understanding the structure and evolution of the Universe. With galaxy observation data growing exponentially, machine learning has become a core technology for this classification task.
Zhijian Luo   +6 more
doaj   +1 more source

Discriminatory Target Learning: Mining Significant Dependence Relationships from Labeled and Unlabeled Data

open access: yesEntropy, 2019
Machine learning techniques have shown superior predictive power, among which Bayesian network classifiers (BNCs) have remained of great interest due to its capacity to demonstrate complex dependence relationships.
Zhi-Yi Duan   +4 more
doaj   +1 more source

Learning protein fitness models from evolutionary and assay-labeled data

open access: yesNature Biotechnology, 2022
Chloe Hsu   +3 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Automatic Labeled LiDAR Data Generation and Distance-Based Ensemble Learning for Human Segmentation

open access: yesIEEE Access, 2019
Following the improvements in deep neural networks, state-of-the-art networks have been proposed for human segmentation using point clouds captured by light detection and ranging.
Wonjik Kim   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

An Open Benchmark Dataset for Forest Characterization from Sentinel-1 and -2 Time Series

open access: yesRemote Sensing
Earth observation satellites offer vast opportunities for quantifying landscapes and regional land cover composition and changes. The integration of artificial intelligence in remote sensing is essential for monitoring significant land cover types like ...
Sarah Hauser   +3 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Data from Osimertinib plus Selumetinib in <i>EGFR</i>-Mutated Non–Small Cell Lung Cancer After Progression on EGFR-TKIs: A Phase Ib, Open-Label, Multicenter Trial (TATTON Part B)

open access: gold, 2023
James Chih‐Hsin Yang   +7 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

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