Results 151 to 160 of about 187,141 (267)

Who labels best? Radiologists, rules, or large language models for CT reports on pulmonary embolism. [PDF]

Eur Radiol Exp
Fink MA, Bischoff A, Atsiatorme E, Kremer A, Kroschke J, Moll M, Stein P, Riebl V, Leichenich T, Kauczor HU, Schlamp K.   +10 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Distinct evolutionary trajectories of two integration centres, the central complex and mushroom bodies, across Heliconiini butterflies. [PDF]

Elife
Farnworth MS, Toh YP, Loupasaki T, Hodge EA, El Jundi B, Montgomery SH.   +5 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Different types of sensory nerve endings in the urinary bladder of mice arising from dorsal root ganglia (DRG) at the thoracolumbar region of vertebral column. [PDF]

Cell Tissue Res
Spencer NJ, Kyloh MA, Travis L, Zagorodnyuk VP, Grundy L, Hibberd T.   +5 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

AMIGO - Guided assignment of ¹³C-methyl labelled proteins. [PDF]

J Biomol NMR
Maass T, Rudolph L, Peters T, Mallagaray A.   +3 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Expediated synthesis of <i>N</i>-acyl-<i>N</i>-alkyl sulfonamide probes for protein proximity labelling.

Org Biomol Chem
Masithi P, Raynal L, O'Brien P, Spicer CD.   +3 more
europepmc   +1 more source

<i>Mycobacterium tuberculosis</i> partitions the Krebs cycle under iron starvation. [PDF]

Elife
Serafini A, Garza-Garcia A, Sorze D, de Carvalho LPS, Manganelli R.   +4 more
europepmc   +1 more source