Results 91 to 100 of about 804,492 (282)

Assessment of utilization of automated systems and laboratory information management systems in clinical microbiology laboratories in Thailand.

PLoS ONE
IntroductionClinical microbiology laboratories are essential for diagnosing and monitoring antimicrobial resistance (AMR). Here, we assessed the systems involved in generating, managing and analyzing blood culture data in these laboratories in an upper ...
Preeyarach Klaytong, Panida Chamawan, Voranadda Srisuphan, Krittiya Tuamsuwan, Phairam Boonyarit, Adisak Sangchankoom, Archawin Rojanawiwat, Aekkawat Unahalekhaka, Kulsumpun Krobanan, Pimrata Leethongdee, Orapan Sripichai, Vanaporn Wuthiekanun, Paul Turner, Direk Limmathurotsakul   +13 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

, 1985
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1234/thumbnail ...

core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Development of Quality Assurance System in Community Hospital Laboratories Region 10

Journal of Associated Medical Sciences, 2015
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Sungkom Kanitvittaya
doaj  

An exogenous encoding sequence based on DNA data storage technology and its application in assisted reproductive technology

Biochemistry and Biophysics Reports
Safety and ethical issues are the primary concerns for assisted reproductive technology (ART). However, confusion and contamination of samples are common problems in embryo laboratories, preimplantation genetic test (PGT) laboratories, and third-party ...
Zhiqing Huang, Taoli Ding, Zixuan Ni, Yujie Zheng, Na Liu, Tuan Li, Wenchang Lian, Beihong Zheng, Yan Sun   +8 more
doaj   +1 more source

Barnes Hospital Bulletin [PDF]

, 1973
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1085/thumbnail ...

core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Benchmarking medical laboratory performance on a global scale

Frontiers in Public Health
Background and aimsLaboratory performance as a relative concept needs repetitive benchmarking for continuous improvement of laboratory procedures and medical processes. Benchmarking as such establishes reference levels as a basis for improvements efforts
Wolfgang Huf, Wolfgang Huf, Mike Mohns, Eni Almeta, Rebecca Lister, Christoph Buchta, Svitlana Demyanets, Svitlana Demyanets, Wolfgang Buchberger, Brigitte Ettl   +9 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source