Results 41 to 50 of about 785,423 (325)

Updated recommendations for HER2 testing in the UK [PDF]

, 2004
This paper serves to update previously published guidance on rationale and methodology for HER2 laboratory testing following the recommendation for the use of HER2 targeted treatment in the management of advanced breast cancer in the UK.
Bartlett, J.M.S., Dowsett, M., Ellis, I.O., Humphreys, S., Jasani, B., Miller, K., Pinder, S.E., Rhodes, A., Walker, R.   +8 more
core   +2 more sources

Cost Effectiveness of Adopted Quality Requirements in Hospital Laboratories

Iranian Journal of Public Health, 2013
Background: The present study was designed in quasi-experiment to assess adoption of the essential clauses of particular clinical laboratory quality management requirements based on international organization for standardization (ISO 15189) in hospital ...
Alneil Hamza, Eltayib Ahmed-Abakur, Elsir Abugroun, Siham Bakhit, Mohamed Holi   +4 more
doaj   +2 more sources

Use and positivity of laboratory tests at Las Tunas provincial hospital

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017
Background: the laboratories must offer the tests to aid doctors in their clinical practice, providing them with the information for the diagnosis, prevention or treatment of diseases.Objective: to describe the use of tests which have been at the doctors’
Jenny de la Caridad Hernández Betancourt, Ariel Segura Fuentes, Jorge Enrique Reyes Membrado, María Mercedes Bello Rodríguez, Bárbara Faustina Martínez Martínez   +4 more
doaj  

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Ensuring accurate testing for human immunodeficiency virus in Myanmar

Bulletin of the World Health Organization, 2015
Problem Until 2005, the quality of rapid diagnostic human immunodeficiency virus (HIV) testing was not monitored and no regular technical support was provided to hospital laboratories in Myanmar.
Latt Latt Kyaw, Ikuma Nozaki, Koji Wada, Khin Yi Oo, Htay Htay Tin, Namiko Yoshihara   +5 more
doaj   +1 more source

Ranunculus ternatus Thunb extract attenuates renal fibrosis of diabetic nephropathy via inhibiting SMYD2

Pharmaceutical Biology, 2022
Context Ranunculus ternatus Thunb (Ranunculaceae), (RTT) is used clinically for the treatment of tuberculosis or as tumour adjuvant therapy, but its potential effect on diabetic nephropathy (DN) has not been studied.
Weiwei Xu, Rui Peng, Siyu Chen, Congcong Wu, Xiaoxiao Wang, Ting Yu, Jiuying Jian, Ni Zhang, Siyang Zuo, Min Chen, Bing Guo, Lirong Liu   +11 more
doaj   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

The future of laboratory medicine - A 2014 perspective. [PDF]

, 2015
Predicting the future is a difficult task. Not surprisingly, there are many examples and assumptions that have proved to be wrong. This review surveys the many predictions, beginning in 1887, about the future of laboratory medicine and its sub ...
FORTINA, PAOLO, Kricka LJ, Park JY, Polsky TG   +3 more
core   +1 more source

Development of a peripheral blood morphology proficiency assessment program using the CellaVision® Proficiency Software

Journal of Laboratory Medicine
Proficiency programs allow hospital laboratories to evaluate and improve diagnostic performance. A cloud-based proficiency program was launched in 2017 to standardize peripheral blood morphology assessments in hospital laboratories across the province of
Ingalls Kimberly, O’Reilly Tish A., Twohig Beverly, Conrad David M.   +3 more
doaj   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source