Results 101 to 110 of about 5,568,953 (372)

Evaluation of the implementation of a quality system in a basic research laboratory: viability and impacts

open access: yesEinstein (São Paulo)
OBJECTIVE: To evaluate the process of implementing a quality management system in a basic research laboratory of a public institution, particularly considering the feasibility and impacts of this improvement.
Hilda Carolina de Jesus Rios Fraga   +4 more
doaj   +1 more source

A Laboratory Oscilloscope

open access: yesReview of Scientific Instruments, 1947
The laboratory oscilloscope is designed primarily for use in the nuclear physics laboratory but is a versatile instrument well suited to general circuit research. It contains a sweep generator with writing speeds ranging from 8 inches per microsecond to 1 inch per millisecond.
V L, FITCH, E W, TITTERTON
openaire   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Shell galaxies as laboratories for testing MOND

open access: yes, 2014
Tests of MOND in ellipticals are relatively rare because these galaxies often lack kinematic tracers in the regions where the MOND effects are significant.
Bartošková, Kateřina   +4 more
core   +1 more source

Investigation of the Status of Laboratory Tests Conducted during Aviation Medical Examination

open access: yesHanggong uju uihakoeji, 2022
Purpose: The medical certification for pilots is required by the aviation safety authority based with the aviation safety act. Methods: In this study, medical examination items of the year of 2021 performed during the aviation medical examination in ...
JoungSoon Jang   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

The Impact of Different DNA Extraction Kits and Laboratories upon the Assessment of Human Gut Microbiota Composition by 16S rRNA Gene Sequencing

open access: yesPLoS ONE, 2014
Introduction Determining bacterial community structure in fecal samples through DNA sequencing is an important facet of intestinal health research. The impact of different commercially available DNA extraction kits upon bacterial community structures has
N. Kennedy   +33 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Chapter 3ModLabs

open access: yesDigital Studies, 2016
This chapter extends from research on the genealogies of modernist laboratories (aesthetic, scientific, and corporate) and their relationship to the formation of contemporary digital-humanities and new-media laboratories and collaboratories.
Dean Irvine
doaj   +1 more source

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