Results 111 to 120 of about 4,260,168 (338)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

A multi-center study of neurofilament assay reliability and inter-laboratory variability

, 2020
Elizabeth Gray, Patrick Oeckl, Maria del Mar Amador, Ulf Andréasson, Jiyan An, Kaj Blennow, Robert Bowser, Maxim De Schaepdryver, Amanda Heslegrave, Jens Kühle, Aleksandra Maleska Maceski, Marleen J.A. Koel‐Simmelink, Foudil Lamari, Vittoria Lombardi, Andrea Malaspina, Irina Nilsson, Koen Poesen, François Salachas, Petra Steinacker, Charlotte E. Teunissen, Philip Van Damme, Henrik Zetterberg, Albert C. Ludolph, Andreas Jeromin, Martin R. Turner, Markus Otto   +25 more
openalex   +2 more sources

Comparison of field and laboratory models of the load bearing capacity in coffee plantations [PDF]

, 2013
Piero Iori, Moacir de Souza Dias, Ayodele Ebenezer Ajayi, Paulo Tácito Gontíjo Guimarães, Paula Sant’Anna Moreira Pais, Maria Luiza de Carvalho Andrade   +5 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Laboratory techniques for the diagnosis of chlamydial infections. [PDF]

, 1991
D Taylor‐Robinson, B J Thomas
openalex   +1 more source

Laboratory manifestations of COVID-19 associated with hemostatic abnormalities

, 2021
Ahmed Elhadi Elsadig, May Mohammed Ali, Alfatih Aboalbasher Yousif   +2 more
openalex   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Science Learning Environments in Higher Education: Researching Classroom, Laboratory, and Field Settings

Education Sciences
This study investigates how science learning environments in higher education have been researched and proposes methodological approaches for future studies.
Katrine Bergkvist Borch, Connie Svabo
doaj   +1 more source