Results 251 to 260 of about 1,629,755 (308)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Improving turnaround times with artificial intelligence in microbiology. [PDF]

J Clin Microbiol
Davidson R, Heinstein C, Patriquin G, Goneau LW, Brown LA, Hill BJ.   +5 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

WHO Global Antimicrobial Resistance Surveillance System (GLASS) for monitoring bloodstream infections due to <i>Candida</i>: findings from a demonstration study. [PDF]

EClinicalMedicine
Marcano Zamora D, Eremin S, Ramon-Pardo P, Forastiero A, Galas M, da Matta DA, Nobrega D, Dobreva Z, Chayakulkeeree M, Shin JH, Zurita S, Chakrabarti A, Chowdhary A, Alastruey-Izquierdo A, Cordoba S, Welna J, Govender NP, Alanio A, Colombo AL, Mareković I, Hilmarsdottir I, Bertagnolio S, Pessoa-Silva CL.   +22 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Implementation and impact of primary HPV testing in cervical cancer screening: Historical perspectives and institutional experience at a large academic medical center. [PDF]

Cancer Cytopathol
Yoda RA, Huang EC.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Reply to Chen et al., "Methodological considerations for the establishment of epidemiological cutoff values for <i>Sporothrix</i> species using CLSI broth microdilution". [PDF]

Antimicrob Agents Chemother
Dos Santos A, Bonifaz A, Bombassaro A, de Sá Machado AC, Rodrigues AM, Borman AM, Chakrabarti A, Chowdary A, Rediguieri B, Johnson EM, Hagen F, Queiroz-Telles F, Gonzalez GM, Garcia-Effron G, Dib Ferreira Gremião I, Meis JF, Possato Fernandes Takahashi J, Pereira Borba Dos Santos L, Melhem MSC, Cappellano P, Nogueira Brilhante RS, Pereira SA, Santos Gonçalvez S, Kidd S, Zhang SX, Rudramurthy S, Rozental S, Cordoba S, de Groot T, Liu W, Wiederhold NP, Meijer EFJ, Lockhart SR, Dufresne PJ.   +33 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Next-generation sequencing and bioinformatics capacity: findings from a multi-country survey to guide the genomics costing tool 2.0. [PDF]

Front Public Health
Bolding A, Argimón S, Whistler T, Kele B, Marklewitz M, Jaguparov A, Musul B, Suresh A, Uplekar S, Le Garrec JS, Campos J, Akande OW.   +11 more
europepmc   +1 more source