Results 21 to 30 of about 6,777 (135)

COVID-19 y VIH/SIDA: implicaciones clínicas y epidemiológicas. Revisión Sistemática

open access: yesKasmera, 2021
La investigación es importante por el impacto global de la sindemia e imparte información de gran utilidad en salud. El objetivo fue describir la relación COVID-19 y VIH/SIDA; implicaciones clínicas y epidemiológicas.
Javier Martin Reyes Baque   +2 more
doaj   +1 more source

ULK4 and CDKN2A polymorphisms influence the risk of developing monoclonal gammopathy of undetermined significance

open access: yesInternational Journal of Cancer, Volume 159, Issue 2, Page 410-422, 15 July 2026.
What's new? Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor to multiple myeloma, sharing substantial genetic features with overt malignancy. Given evidence implicating autophagy in myeloma risk, this study examined whether genetic variations in autophagy‐related genes influence MGUS susceptibility.
José Manuel Sánchez‐Maldonado   +54 more
wiley   +1 more source

A Robust and Comprehensive Study of the Molecular and Genetic Basis of Neurodevelopmental Delay in a Sample of 3244 Patients, Evaluated by Exome Analysis in a Latin Population

open access: yesDiagnostics
Background and Objectives: Neurodevelopmental disorders (NDDs), including developmental delay (DD), autism spectrum disorder (ASD), intellectual disability (ID), attention-deficit/hyperactivity disorder (ADHD), and specific learning disorders, affect 15%
Julian Lamilla   +11 more
doaj   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

open access: yesArthritis &Rheumatology, Volume 78, Issue 7, Page 1535-1553, July 2026.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla   +13 more
wiley   +1 more source

Development and performance evaluation of a qPCR-based assay for the fully automated detection of group B Streptococcus (GBS) on the Panther Fusion Open Access system

open access: yesMicrobiology Spectrum
Streptococcus agalactiae [group B Streptococcus (GBS)] poses a major threat as the primary cause of early-onset neonatal invasive disease, particularly when mothers are colonized rectovaginally.
Andy Caballero Méndez   +7 more
doaj   +1 more source

Comparative bioavailability of a novel fixed‐dose combination of ticagrelor and acetylsalicylic acid

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 7, July 2026.
Abstract Dual antiplatelet therapy (DAPT) with acetylsalicylic acid (hereafter referred to as ASA) and ticagrelor is the standard of care for secondary prevention for atherothrombotic events, particularly in patients with noncardioembolic cerebrovascular disease or coronary artery disease.
Susana Tera‐Ponce   +8 more
wiley   +1 more source

Recreational Drug Use at a Music Festival: A Dual Approach Using Hair Biomarkers Analysis and Participant Self‐Reported Drug Use

open access: yesDrug Testing and Analysis, Volume 18, Issue 7, Page 831-840, July 2026.
Combined self‐report and hair analysis in festival attendees (n = 249) revealed substantial discrepancies in drug use reporting, particularly for stimulants and dissociatives. This integrated approach enhances detection of poly‐drug use and provides a more reliable basis for monitoring and harm‐reduction strategies.
A. Y. Simão   +4 more
wiley   +1 more source

Survival analysis and prognostic factors of mature T-cell and natural killer/T-cell neoplasms in Colombian patients from 2008-2025

open access: yesFrontiers in Oncology
BackgroundT-cell lymphomas show global variation, but research in Latin America remains limited. The main outcome This study aimed to determine, subtype distribution frequency, treatment, and overall survival of T-cell lymphoma.MethodsWe conducted a ...
Juan F. Combariza-Vallejo   +8 more
doaj   +1 more source

Integrative Transcriptomic and Functional Analysis of PKMYT1 Reveals a Potential Therapeutic Target in Chronic Lymphocytic Leukemia

open access: yesHematological Oncology, Volume 44, Issue 4, July 2026.
ABSTRACT Chronic lymphocytic leukemia (CLL) is a clinically and molecularly heterogeneous disease. PKMYT1, a G2/M cell cycle kinase, has been implicated in tumor progression in several cancers, but its role in CLL remains unclear. We evaluated PKMYT1 expression in primary CLL samples and analyzed associations with cytogenetic features and clinical ...
Elizabete Cristina Iseke Bispo   +6 more
wiley   +1 more source

Detección serológica del Virus Papiloma Humano en mujeres mayores de 20 años. Caso sector “Gary Esparza”, Babahoyo, Ecuador

open access: yesCiencia UNEMI, 2017
The Human Papilloma Virus (HPV) is a virus that has a double-stranded DNA genome belonging to the Papovaviridae family. It has oncogenic ability in a variety of mammals, especially man, in which more than 200 serotypes are known and represents one of ...
Rodas-Neira, Edgar   +11 more
doaj  

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