Results 31 to 40 of about 579,668 (169)

ULK4 and CDKN2A polymorphisms influence the risk of developing monoclonal gammopathy of undetermined significance

open access: yesInternational Journal of Cancer, Volume 159, Issue 2, Page 410-422, 15 July 2026.
What's new? Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor to multiple myeloma, sharing substantial genetic features with overt malignancy. Given evidence implicating autophagy in myeloma risk, this study examined whether genetic variations in autophagy‐related genes influence MGUS susceptibility.
José Manuel Sánchez‐Maldonado   +54 more
wiley   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

open access: yesArthritis &Rheumatology, Volume 78, Issue 7, Page 1535-1553, July 2026.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla   +13 more
wiley   +1 more source

Survival analysis and prognostic factors of mature T-cell and natural killer/T-cell neoplasms in Colombian patients from 2008-2025

open access: yesFrontiers in Oncology
BackgroundT-cell lymphomas show global variation, but research in Latin America remains limited. The main outcome This study aimed to determine, subtype distribution frequency, treatment, and overall survival of T-cell lymphoma.MethodsWe conducted a ...
Juan F. Combariza-Vallejo   +8 more
doaj   +1 more source

Comparative bioavailability of a novel fixed‐dose combination of ticagrelor and acetylsalicylic acid

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 7, July 2026.
Abstract Dual antiplatelet therapy (DAPT) with acetylsalicylic acid (hereafter referred to as ASA) and ticagrelor is the standard of care for secondary prevention for atherothrombotic events, particularly in patients with noncardioembolic cerebrovascular disease or coronary artery disease.
Susana Tera‐Ponce   +8 more
wiley   +1 more source

Detección serológica del Virus Papiloma Humano en mujeres mayores de 20 años. Caso sector “Gary Esparza”, Babahoyo, Ecuador

open access: yesCiencia UNEMI, 2017
The Human Papilloma Virus (HPV) is a virus that has a double-stranded DNA genome belonging to the Papovaviridae family. It has oncogenic ability in a variety of mammals, especially man, in which more than 200 serotypes are known and represents one of ...
Rodas-Neira, Edgar   +11 more
doaj  

Recreational Drug Use at a Music Festival: A Dual Approach Using Hair Biomarkers Analysis and Participant Self‐Reported Drug Use

open access: yesDrug Testing and Analysis, Volume 18, Issue 7, Page 831-840, July 2026.
Combined self‐report and hair analysis in festival attendees (n = 249) revealed substantial discrepancies in drug use reporting, particularly for stimulants and dissociatives. This integrated approach enhances detection of poly‐drug use and provides a more reliable basis for monitoring and harm‐reduction strategies.
A. Y. Simão   +4 more
wiley   +1 more source

Campylobacter spp. Prevalence in Santiago, Chile: A Study Based on Molecular Detection in Clinical Stool Samples from 2014 to 2019

open access: yesPathogens, 2023
Campylobacter spp. is an emerging cause of infectious diarrhea worldwide. In South American countries such as Chile, its prevalence is underestimated due to inadequate detection methods.
Lorena Porte   +6 more
doaj   +1 more source

Integrative Transcriptomic and Functional Analysis of PKMYT1 Reveals a Potential Therapeutic Target in Chronic Lymphocytic Leukemia

open access: yesHematological Oncology, Volume 44, Issue 4, July 2026.
ABSTRACT Chronic lymphocytic leukemia (CLL) is a clinically and molecularly heterogeneous disease. PKMYT1, a G2/M cell cycle kinase, has been implicated in tumor progression in several cancers, but its role in CLL remains unclear. We evaluated PKMYT1 expression in primary CLL samples and analyzed associations with cytogenetic features and clinical ...
Elizabete Cristina Iseke Bispo   +6 more
wiley   +1 more source

Steatotic Liver Disease at Primary Biliary Cholangitis Diagnosis: Association With Ursodeoxycholic Acid Response and Outcomes

open access: yesLiver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background and Aim Steatotic liver disease (SLD) is becoming increasingly prevalent, leading to a higher frequency of primary biliary cholangitis (PBC) cases coexisting with SLD. However, data on its impact in patients with PBC remain scarce.
María Del Barrio   +38 more
wiley   +1 more source

Costos operativos y rentabilidad de los exámenes de laboratorio clínico de un centro médico privado de Bagua, 2025 [PDF]

open access: yes
El presente estudio tuvo como objetivo determinar el efecto de los costos operativos en la rentabilidad de los exámenes de laboratorio clínico de un centro médico privado en Bagua, 2025. Se llevó a cabo una investigación de carácter descriptivo, aplicado,
Sánchez Carrera,Luz Dayeli   +1 more
core   +1 more source

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