Results 91 to 100 of about 7,625,703 (311)
University of California Radiation Laboratory Reports UCRL-1729
Quarterly summary report of studies conducted through the Radiation Laboratory, University of California.
Lawrence Radiation Laboratory
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Brookhaven National Laboratory Reports
Report issued by the Brookhaven National Laboratory discussing high-pressured gamma loops. As stated in the introduction, "this latest endeavor involved three test cells, a gamma irradiation pool and supporting equipment, as well as an enlarged high ...
Brookhaven National Laboratory
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
University of California Radiation Laboratory Reports UCRL-1610
Quarterly summary report of studies conducted through the Radiation Laboratory, University of California.
University of California. Radiation Laboratory.
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Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
University of California Radiation Laboratory Reports UCRL-1632
Quarterly summary report of studies conducted through the Radiation Laboratory, University of California.
University of California. Radiation Laboratory.
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
From bench to bedside: three imperatives for making the digital laboratory a reality
Alia Manetta
doaj +1 more source

