Results 101 to 110 of about 7,625,703 (311)

Artificial Laboratories.

open access: yesAI Mag., 1989
An artificial laboratory is a hypothetical computing environment of the future that would integrate mathematical and statistical tools with AI methods to assist in computer modeling and simulation. An integrated approach of this kind has great potential for accelerating the rate of scientific discovery.
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Profiles of systemic lupus erythematosus patients with co-existing sickle cell disease: a coincidence or true association?

open access: yesRheumatology
Introduction Systemic lupus erythematosus (SLE) and sickle cell disease (SCD) are distinct multisystemic diseases that commonly affect blacks. There are few reports of their co-existence in Western literature and a paucity of reports in Sub-Saharan ...
Hakeem Babatunde Olaosebikan   +7 more
doaj   +1 more source

University of California Radiation Laboratory Reports UCRL-1854

open access: yes, 1952
Quarterly summary report of studies conducted through the University of California Radiation Laboratory.
University of California. Radiation Laboratory.
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Challenges and Alternative Solutions for Implementing Chemistry Practicums in Public High Schools

open access: yesJTK (Jurnal Tadris Kimiya)
Laboratories play a crucial role in enhancing learning experiences, verifying scientific concepts, and solving problems through scientific methods. However, the implementation of chemistry practicums in schools often faces significant challenges.
Suci Nabila   +5 more
doaj   +1 more source

Argonne National Laboratory Report ANL-5256

open access: yes, 1954
Report issued by the Argonne National Laboratory discussing meteorological data collected between 1952 and 1953. Wind, temperature, pressure, and precipitation studies are presented.
Turner, Louis Alexander, 1898-   +1 more
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1985

open access: yes, 1986
Annual report of the Marine Biological Laboratory in Woods Hole. 1985.
Marine Biological Laboratory (Woods Hole MA)
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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